TY - JOUR
T1 - Correlation of lesional skin corneometry values with serum E-selectin levels and disease severity in patients affected by plaque-type psoriasis
T2 - Recovery after effective therapy
AU - Carducci, M.
AU - Mussi, A.
AU - Bonifati, C.
AU - Tomaselli, R.
AU - Onorati, M. T.
AU - Trento, E.
AU - Ameglio, F.
PY - 1995
Y1 - 1995
N2 - Ten subjects with plaque-type psoriasis (5 females, 5 males, median age 47, range 20-71 years, median psoriasis area and severity index [PASI] score=15.5, range 8.1-23.0) were observed before (week 0) and at the second and sixth week after starting treatment (PASI=10.5, range 7.8-14.6; PASI=8.5, range 1.6-11.6, respectively). At each of these times, the patients were evaluated for both lesional and unlesional skin corneometry and serum E- selectin values, previously shown to be increased in psoriatic subjects. At time 0, both the corneometry and the E-selectin values were significantly correlated with the PASI, infiltration and desquamation scores. As expected, the corneometry was statistically higher in the unlesional than in the lesional areas (p
AB - Ten subjects with plaque-type psoriasis (5 females, 5 males, median age 47, range 20-71 years, median psoriasis area and severity index [PASI] score=15.5, range 8.1-23.0) were observed before (week 0) and at the second and sixth week after starting treatment (PASI=10.5, range 7.8-14.6; PASI=8.5, range 1.6-11.6, respectively). At each of these times, the patients were evaluated for both lesional and unlesional skin corneometry and serum E- selectin values, previously shown to be increased in psoriatic subjects. At time 0, both the corneometry and the E-selectin values were significantly correlated with the PASI, infiltration and desquamation scores. As expected, the corneometry was statistically higher in the unlesional than in the lesional areas (p
KW - corneometry
KW - PASI
KW - psoriasis
KW - serum E-selectin
KW - treatment
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M3 - Article
C2 - 7560436
AN - SCOPUS:0029082405
VL - 22
SP - 475
EP - 479
JO - Journal of Dermatology
JF - Journal of Dermatology
SN - 0385-2407
IS - 7
ER -