Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa

Maurizio Battaglia Parodi; Carlo La Spina; Giacinto Triolo; Fulvio Riccieri; Luisa Pierro; Marco Gagliardi; Francesco Bandello

doi:10.1007/s00417-015-3185-x

Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa

Maurizio Battaglia Parodi, Carlo La Spina, Giacinto Triolo, Fulvio Riccieri, Luisa Pierro, Marco Gagliardi, Francesco Bandello

Research output: Contribution to journal › Article

Abstract

Purpose: To describe the morphological macular changes detected by spectral domain optical coherence tomography (SD-OCT) in eyes with retinitis pigmentosa (RP) and to analyze their correlation with the visual function. Methods: Twenty-two patients (44 eyes) patients affected by RP were recruited. The following structures were evaluated on SD-OCT: outer plexiform layer (OPL), outer nuclear layer (ONL), external limiting membrane (ELM), photoreceptor inner/outer segment (IS/OS) junction, photoreceptor outer segment/retinal pigmented epithelium (OS/RPE) junction, inner limiting membrane thickening (ILMT), ganglion cell complex (GCC), and cystoid macular edema (CME). The relation between each SD-OCT finding and BCVA was evaluated at uni- and multivariate analysis. Results: Mean age and mean best-corrected visual acuity (BCVA) were 51 ± 17.5 years and 0.4 ± 0.5 LogMAR, respectively. Univariate linear regression model revealed a correlation between BCVA and the absence of ELM, IS/OS, ONL, and OS/RPE layers (R2 values were, respectively, 0.51, 0.57, 0.48, and 0.68, with p values all

Original language	English
Pages (from-to)	1275 - 1279
Number of pages	5
Journal	Graefe's Archive for Clinical and Experimental Ophthalmology
Volume	254
Issue number	7
DOIs	https://doi.org/10.1007/s00417-015-3185-x
Publication status	Published - Jul 1 2016

Keywords

Retinitis pigmentosa
Spectral domain OCT
Visual acuity

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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Battaglia Parodi, M., La Spina, C., Triolo, G., Riccieri, F., Pierro, L., Gagliardi, M., & Bandello, F. (2016). Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa. Graefe's Archive for Clinical and Experimental Ophthalmology, 254(7), 1275 - 1279. https://doi.org/10.1007/s00417-015-3185-x

Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa. / Battaglia Parodi, Maurizio; La Spina, Carlo; Triolo, Giacinto; Riccieri, Fulvio; Pierro, Luisa ; Gagliardi, Marco ; Bandello, Francesco.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 254, No. 7, 01.07.2016, p. 1275 - 1279.

Research output: Contribution to journal › Article

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