Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 1275 - 1279 |
| Number of pages | 5 |
| Journal | Graefe's Archive for Clinical and Experimental Ophthalmology |
| Volume | 254 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 1 2016 |
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Keywords
- Retinitis pigmentosa
- Spectral domain OCT
- Visual acuity
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
Cite this
Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa. / Battaglia Parodi, Maurizio; La Spina, Carlo; Triolo, Giacinto; Riccieri, Fulvio; Pierro, Luisa; Gagliardi, Marco; Bandello, Francesco.
In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 254, No. 7, 01.07.2016, p. 1275 - 1279.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Correlation of SD-OCT findings and visual function in patients with retinitis pigmentosa
AU - Battaglia Parodi, Maurizio
AU - La Spina, Carlo
AU - Triolo, Giacinto
AU - Riccieri, Fulvio
AU - Pierro, Luisa
AU - Gagliardi, Marco
AU - Bandello, Francesco
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Purpose: To describe the morphological macular changes detected by spectral domain optical coherence tomography (SD-OCT) in eyes with retinitis pigmentosa (RP) and to analyze their correlation with the visual function. Methods: Twenty-two patients (44 eyes) patients affected by RP were recruited. The following structures were evaluated on SD-OCT: outer plexiform layer (OPL), outer nuclear layer (ONL), external limiting membrane (ELM), photoreceptor inner/outer segment (IS/OS) junction, photoreceptor outer segment/retinal pigmented epithelium (OS/RPE) junction, inner limiting membrane thickening (ILMT), ganglion cell complex (GCC), and cystoid macular edema (CME). The relation between each SD-OCT finding and BCVA was evaluated at uni- and multivariate analysis. Results: Mean age and mean best-corrected visual acuity (BCVA) were 51 ± 17.5 years and 0.4 ± 0.5 LogMAR, respectively. Univariate linear regression model revealed a correlation between BCVA and the absence of ELM, IS/OS, ONL, and OS/RPE layers (R2 values were, respectively, 0.51, 0.57, 0.48, and 0.68, with p values all
AB - Purpose: To describe the morphological macular changes detected by spectral domain optical coherence tomography (SD-OCT) in eyes with retinitis pigmentosa (RP) and to analyze their correlation with the visual function. Methods: Twenty-two patients (44 eyes) patients affected by RP were recruited. The following structures were evaluated on SD-OCT: outer plexiform layer (OPL), outer nuclear layer (ONL), external limiting membrane (ELM), photoreceptor inner/outer segment (IS/OS) junction, photoreceptor outer segment/retinal pigmented epithelium (OS/RPE) junction, inner limiting membrane thickening (ILMT), ganglion cell complex (GCC), and cystoid macular edema (CME). The relation between each SD-OCT finding and BCVA was evaluated at uni- and multivariate analysis. Results: Mean age and mean best-corrected visual acuity (BCVA) were 51 ± 17.5 years and 0.4 ± 0.5 LogMAR, respectively. Univariate linear regression model revealed a correlation between BCVA and the absence of ELM, IS/OS, ONL, and OS/RPE layers (R2 values were, respectively, 0.51, 0.57, 0.48, and 0.68, with p values all
KW - Retinitis pigmentosa
KW - Spectral domain OCT
KW - Visual acuity
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U2 - 10.1007/s00417-015-3185-x
DO - 10.1007/s00417-015-3185-x
M3 - Article
VL - 254
SP - 1275
EP - 1279
JO - Graefe's Archive for Clinical and Experimental Ophthalmology
JF - Graefe's Archive for Clinical and Experimental Ophthalmology
SN - 0721-832X
IS - 7
ER -