Abstract
Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.
| Original language | English |
|---|---|
| Article number | 1 |
| Pages (from-to) | 1-4 |
| Number of pages | 4 |
| Journal | BMC Musculoskeletal Disorders |
| Volume | 3 |
| DOIs | |
| Publication status | Published - Jul 19 2002 |
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Keywords
- Pain
- Pain measurement
- Rheumatoid arthritis
ASJC Scopus subject areas
- Medicine(all)
Cite this
Correlation of the score for subjective pain with physical disability,clinical and radiographic scores in recent onset rheumatoid arthritis. / Sarzi-Puttini, Piercarlo; Fiorini, Tania; Panni, Benedetta; Turiel, Maurizio; Cazzola, Marco; Atzeni, Fabiola.
In: BMC Musculoskeletal Disorders, Vol. 3, 1, 19.07.2002, p. 1-4.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Correlation of the score for subjective pain with physical disability,clinical and radiographic scores in recent onset rheumatoid arthritis
AU - Sarzi-Puttini, Piercarlo
AU - Fiorini, Tania
AU - Panni, Benedetta
AU - Turiel, Maurizio
AU - Cazzola, Marco
AU - Atzeni, Fabiola
PY - 2002/7/19
Y1 - 2002/7/19
N2 - Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.
AB - Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.
KW - Pain
KW - Pain measurement
KW - Rheumatoid arthritis
UR - http://www.scopus.com/inward/record.url?scp=12344276319&partnerID=8YFLogxK
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U2 - 10.1186/1471-2474-3-1
DO - 10.1186/1471-2474-3-1
M3 - Article
AN - SCOPUS:12344276319
VL - 3
SP - 1
EP - 4
JO - BMC Musculoskeletal Disorders
JF - BMC Musculoskeletal Disorders
SN - 1471-2474
M1 - 1
ER -