Correlation of the score for subjective pain with physical disability,clinical and radiographic scores in recent onset rheumatoid arthritis

Piercarlo Sarzi-Puttini, Tania Fiorini, Benedetta Panni, Maurizio Turiel, Marco Cazzola, Fabiola Atzeni

Research output: Contribution to journalArticle

Abstract

Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.

Original languageEnglish
Article number1
Pages (from-to)1-4
Number of pages4
JournalBMC Musculoskeletal Disorders
Volume3
DOIs
Publication statusPublished - Jul 19 2002

Fingerprint

Rheumatoid Arthritis
Pain
Rheumatoid Factor
Visual Analog Scale
C-Reactive Protein
Health
Joints
Foot Joints
Regression Analysis
Hand Joints
Wrist Joint
Diagnostic Self Evaluation
Blood Sedimentation
Pain Measurement
Cross-Sectional Studies
Demography
Surveys and Questionnaires

Keywords

  • Pain
  • Pain measurement
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Correlation of the score for subjective pain with physical disability,clinical and radiographic scores in recent onset rheumatoid arthritis. / Sarzi-Puttini, Piercarlo; Fiorini, Tania; Panni, Benedetta; Turiel, Maurizio; Cazzola, Marco; Atzeni, Fabiola.

In: BMC Musculoskeletal Disorders, Vol. 3, 1, 19.07.2002, p. 1-4.

Research output: Contribution to journalArticle

Sarzi-Puttini, Piercarlo ; Fiorini, Tania ; Panni, Benedetta ; Turiel, Maurizio ; Cazzola, Marco ; Atzeni, Fabiola. / Correlation of the score for subjective pain with physical disability,clinical and radiographic scores in recent onset rheumatoid arthritis. In: BMC Musculoskeletal Disorders. 2002 ; Vol. 3. pp. 1-4.
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abstract = "Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71{\%} rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8{\%} of the variation in pain intensity score, morning stiffness 10.7{\%}, CRP 4.0{\%}, HAQ 3.8{\%} and Larsen-Dale scores explained 2.1{\%}; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.",
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AU - Sarzi-Puttini, Piercarlo

AU - Fiorini, Tania

AU - Panni, Benedetta

AU - Turiel, Maurizio

AU - Cazzola, Marco

AU - Atzeni, Fabiola

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AB - Background: To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen radiographic scores and Health Assessment Questionnaire (HAQ); in patients with severe rheumatoid arthritis (RA) with a disease duration of less than 3 years. Methods: In this cross sectional study of 105 patients with RA (76 women, 29 men: mean age 50.93; mean disease duration 15.86 months; 71% rheumatoid factor positive) subjective pain was assessed according to the Visual Analog Scale (VAS). Correlation coefficients between pain score and disease activity measures (patients' global assessment of disease by VAS, number of tender and swollen joints, morning stiffness, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP] and titre of rheumatoid factor, radiographic evaluations (Larsen-Dale scores for radiographic damage of the small joints of the hands, wrist and feet), disability measures (health assessment questionnaire [HAQ]), and demographic variables were calculated; hierarchical regression analysis was done with subjective pain score as the dependent variable. Results: The Spearman's correlation coefficient comparing subjective pain and HAQ was 0.421 (p <0.001), between subjective pain and global assessment of disease and morning stiffness was 0.573 (p <0.001) and 0.427 (p <0.001) respectively, and between pain and number of tender and swollen joints 0.037 and 0.050 respectively (p > 0.05). In regression analysis, global assessment of disease by patients explained 32.8% of the variation in pain intensity score, morning stiffness 10.7%, CRP 4.0%, HAQ 3.8% and Larsen-Dale scores explained 2.1%; other variables were not significant in the model. Conclusions: Pain scores of patients with early severe rheumatoid arthritis are correlated at higher levels with patients' global assessment of disease and with morning stiffness rather than with radiographic or other clinical variables such as number of tender and swollen joints.

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