Correlazione tra la micro-alternanza dell'onda T ed i parametri patologici e fisiologici in pazienti con cardiopatia ischemica, in età geriatrica e non

Translated title of the contribution: Correlations between T-wave's alternation and physiopathological parameters in patients with ischemic heart disease

Veronica De Crescenzo, M. Santomauro, A. Borrelli, D. F. Vitale, V. Coletta, V. Iovino, P. Diana, C. Visconti, M. Chiariello, G. Gerundo, F. Rengo, I. Simione

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Abstract

Objective: The T-wave's alternation (mTWA) is an available test with high negative predictive value to stratify the arrhythmic risk. Aim of our research was to verify the existence of correlations among the presence of mTWA and some physiopathological parameters in a selected population of patients suffering from documented ischemic heart disease. Methods: We enrolled 33 patients: 16 adults and 17 geriatrics. The evaluation of the mTWA was effected in wash-out from β-blockers. We correlated sex, EF, severity of the coronary illness, presence of DCM and age, to the presence/absence of mTWA. Results: The analysis of the alternation was positive in 11 patients (7 patients in geriatric age and 4 adults). Statistical analysis showed significant differences for EF, presence of DCM and WMSI, while for sex (p = 0.757), age (p = 0.972) and number of coronary exposed to PTCA vessels (p = 0.558) the statistical significance was not reached. The multivaried analysis showed that the only variable meaningfully associated to the presence of positive mTWA was the EF (p = 0.035). The age didn't show meaningful degrees of association with the positiveness of the mTWA neither to the univaried analysis neither to the logistic analysis. Conclusions: Also with the limitations of the narrow case, this study confirms that the presence of positive mTWA joins to low values of FE and seems to be not conditioned by the age. The introduction in the clinical practice of the evaluation of the mTWA offers the possibility to get a punctual bloodless evaluation of the arrhythmic risk that represents an advantage for all the patients and obtains a greater value in the elderly patients.

Original languageItalian
Pages (from-to)164-169
Number of pages6
JournalGiornale di Gerontologia
Volume55
Issue number3
Publication statusPublished - Jun 2007

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ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

De Crescenzo, V., Santomauro, M., Borrelli, A., Vitale, D. F., Coletta, V., Iovino, V., Diana, P., Visconti, C., Chiariello, M., Gerundo, G., Rengo, F., & Simione, I. (2007). Correlazione tra la micro-alternanza dell'onda T ed i parametri patologici e fisiologici in pazienti con cardiopatia ischemica, in età geriatrica e non. Giornale di Gerontologia, 55(3), 164-169.