Studio dell'eccitabilita corticale in un paziente con epilessia parziale e mioclono corticale

Translated title of the contribution: Cortical excitability in a patient with cortical myoclonus

M. Inghilleri, D. Mattia, P. Quarato, A. Berardelli, M. Manfredi

Research output: Contribution to journalArticle

Abstract

Transcranial stimulation technique was used to analysed the excitability of motor cortex in a patient with focal epilepsy and cortical myoclonus originating from the right motor cortex. In epileptic motor cortex (50%) the motor threshold to single magnetic stimuli and not to electrical ones was higher then the contralateral side; a short lasting silent period (50 ms) was elicited by magnetic shocks in the epileptic cortex; using the double shocks technique a reduced cortico-cortical inhibition was evident. These findings are consistent with an asymmetry in cortical excitability; an impaired inhibition in the epileptic motor cortex is supposed as the underlined mechanism.

Original languageItalian
Pages (from-to)309-312
Number of pages4
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number99
Publication statusPublished - 1997

Fingerprint

Myoclonus
Motor Cortex
Shock
Partial Epilepsy
Cortical Excitability

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

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AU - Inghilleri, M.

AU - Mattia, D.

AU - Quarato, P.

AU - Berardelli, A.

AU - Manfredi, M.

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Y1 - 1997

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AB - Transcranial stimulation technique was used to analysed the excitability of motor cortex in a patient with focal epilepsy and cortical myoclonus originating from the right motor cortex. In epileptic motor cortex (50%) the motor threshold to single magnetic stimuli and not to electrical ones was higher then the contralateral side; a short lasting silent period (50 ms) was elicited by magnetic shocks in the epileptic cortex; using the double shocks technique a reduced cortico-cortical inhibition was evident. These findings are consistent with an asymmetry in cortical excitability; an impaired inhibition in the epileptic motor cortex is supposed as the underlined mechanism.

KW - Cortical silent period

KW - Epilepsy

KW - THS

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