Abstract
Fixation-off sensitivity (FOS) refers to seizures or EEG abnormalities elicited by the elimination of central vision/fixation, even in the presence of light.1 Typically, a paroxysmal discharge occurs within 1–3 seconds of eye closure, persists throughout the eye-closed state, and disappears immediately on eye opening.2
FOS occurs mainly in childhood occipital epilepsies.1 It has also been reported in generalized andfocalepilepsiesofstructural/unknownetiology,eyelidmyocloniawithabsences,andrarely in nonepileptic individuals.3
We describe a patient with FOS associated with cortical myoclonic tremor (CMT) so intense and severe at wake-sleep transition to cause sleep-onset insomnia as the main complaint.
FOS occurs mainly in childhood occipital epilepsies.1 It has also been reported in generalized andfocalepilepsiesofstructural/unknownetiology,eyelidmyocloniawithabsences,andrarely in nonepileptic individuals.3
We describe a patient with FOS associated with cortical myoclonic tremor (CMT) so intense and severe at wake-sleep transition to cause sleep-onset insomnia as the main complaint.
Original language | English |
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Pages (from-to) | 1061-1063 |
Number of pages | 3 |
Journal | Neurology |
Volume | 91 |
Issue number | 23 |
DOIs | |
Publication status | Published - Dec 4 2018 |