Abstract
In human arm amputees, a significant relationship was found between the amount of reorganization in the primary somato-sensory cortex, and the amount of body surface from which painful stimuli evoked sensations that were perceived to be emanating from the now missing extremity, i.e. the phantom limb. This mislocalization could be evoked almost equally from stimulation of either side of the body. Based on these findings obtained by magnetic source imaging and psychophysical testing in eight amputees, it is concluded that the extent of the generally known cortical reorganization contralateral to the amputation is an indicator of more widespread plastic changes in the brain involving bilateral pathways.
| Original language | English |
|---|---|
| Pages (from-to) | 262-264 |
| Number of pages | 3 |
| Journal | Neuroscience Letters |
| Volume | 201 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Dec 15 1995 |
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Keywords
- Amputation
- Cortex
- Mislocalization
- Phantom limb
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb. / Knecht, S.; Henningsen, H.; Elbert, T.; Flor, H.; Höhling, C.; Pantev, C.; Birbaumer, N.; Taub, E.
In: Neuroscience Letters, Vol. 201, No. 3, 15.12.1995, p. 262-264.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb
AU - Knecht, S.
AU - Henningsen, H.
AU - Elbert, T.
AU - Flor, H.
AU - Höhling, C.
AU - Pantev, C.
AU - Birbaumer, N.
AU - Taub, E.
PY - 1995/12/15
Y1 - 1995/12/15
N2 - In human arm amputees, a significant relationship was found between the amount of reorganization in the primary somato-sensory cortex, and the amount of body surface from which painful stimuli evoked sensations that were perceived to be emanating from the now missing extremity, i.e. the phantom limb. This mislocalization could be evoked almost equally from stimulation of either side of the body. Based on these findings obtained by magnetic source imaging and psychophysical testing in eight amputees, it is concluded that the extent of the generally known cortical reorganization contralateral to the amputation is an indicator of more widespread plastic changes in the brain involving bilateral pathways.
AB - In human arm amputees, a significant relationship was found between the amount of reorganization in the primary somato-sensory cortex, and the amount of body surface from which painful stimuli evoked sensations that were perceived to be emanating from the now missing extremity, i.e. the phantom limb. This mislocalization could be evoked almost equally from stimulation of either side of the body. Based on these findings obtained by magnetic source imaging and psychophysical testing in eight amputees, it is concluded that the extent of the generally known cortical reorganization contralateral to the amputation is an indicator of more widespread plastic changes in the brain involving bilateral pathways.
KW - Amputation
KW - Cortex
KW - Mislocalization
KW - Phantom limb
UR - http://www.scopus.com/inward/record.url?scp=0029565035&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029565035&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(95)12186-2
DO - 10.1016/0304-3940(95)12186-2
M3 - Article
C2 - 8786855
AN - SCOPUS:0029565035
VL - 201
SP - 262
EP - 264
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 3
ER -