Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb

S. Knecht, H. Henningsen, T. Elbert, H. Flor, C. Höhling, C. Pantev, N. Birbaumer, E. Taub

Research output: Contribution to journalArticle

Abstract

In human arm amputees, a significant relationship was found between the amount of reorganization in the primary somato-sensory cortex, and the amount of body surface from which painful stimuli evoked sensations that were perceived to be emanating from the now missing extremity, i.e. the phantom limb. This mislocalization could be evoked almost equally from stimulation of either side of the body. Based on these findings obtained by magnetic source imaging and psychophysical testing in eight amputees, it is concluded that the extent of the generally known cortical reorganization contralateral to the amputation is an indicator of more widespread plastic changes in the brain involving bilateral pathways.

Original languageEnglish
Pages (from-to)262-264
Number of pages3
JournalNeuroscience Letters
Volume201
Issue number3
DOIs
Publication statusPublished - Dec 15 1995

Keywords

  • Amputation
  • Cortex
  • Mislocalization
  • Phantom limb

ASJC Scopus subject areas

  • Neuroscience(all)

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    Knecht, S., Henningsen, H., Elbert, T., Flor, H., Höhling, C., Pantev, C., Birbaumer, N., & Taub, E. (1995). Cortical reorganization in human amputees and mislocalization of painful stimuli to the phantom limb. Neuroscience Letters, 201(3), 262-264. https://doi.org/10.1016/0304-3940(95)12186-2