Cortical sources of resting EEG rhythms in mild cognitive impairment and subjective memory complaint

Claudio Babiloni, Pieter Jelle Visser, Giovanni Frisoni, Peter Paul De Deyn, Lorena Bresciani, Vesna Jelic, Guy Nagels, Guido Rodriguez, Paolo M. Rossini, Fabrizio Vecchio, Danilo Colombo, Frans Verhey, Lars Olof Wahlund, Flavio Nobili

Research output: Contribution to journalArticlepeer-review


Are cortical electroencephalographic (EEG) rhythms altered in amnesic and non-amnesic mild cognitive impairment (MCI), subjective memory complaint (SMC), and healthy elderly (Nold) subjects? Eyes-closed resting EEG was recorded in 79 Nold, 53 SMC, 51 non-amnesic MCI, and 92 amnesic MCI subjects. EEG rhythms of interest were delta (2-4. Hz), theta (4-8. Hz), alpha 1 (8-10.5. Hz), alpha 2 (10.5-13. Hz), beta 1 (13-20. Hz), beta 2 (20-30. Hz) and gamma (30-40. Hz). Cortical EEG sources were estimated by standardized low resolution brain electromagnetic tomography (sLORETA). Results showed that (i) the frontal delta sources were greater in amplitude in the amnesic MCI and SMC subjects than in the Nold subjects (p

Original languageEnglish
Pages (from-to)1787-1798
Number of pages12
JournalNeurobiology of Aging
Issue number10
Publication statusPublished - Oct 2010


  • Alzheimer's disease (AD)
  • Electroencephalography (EEG)
  • Mild cognitive impairment (MCI)
  • SLORETA (standardized low resolution brain electromagnetic tomography)
  • Subjective memory complaint (SMC)

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Ageing
  • Developmental Biology
  • Geriatrics and Gerontology


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