Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy

Claudio Babiloni; Paola Buffo; Fabrizio Vecchio; Paolo Onorati; Chiara Muratori; Stefano Ferracuti; Paolo Roma; Michele Battuello; Nicole Donato; Giuseppe Noce; Francesco Di Campli; Laura Gianserra; Elisabetta Teti; Antonio Aceti; Andrea Soricelli; Magdalena Viscione; Massimo Andreoni; Paolo M. Rossini; Alfredo Pennica

doi:10.1016/j.clinph.2014.01.024

Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy

Claudio Babiloni, Paola Buffo, Fabrizio Vecchio, Paolo Onorati, Chiara Muratori, Stefano Ferracuti, Paolo Roma, Michele Battuello, Nicole Donato, Giuseppe Noce, Francesco Di Campli, Laura Gianserra, Elisabetta Teti, Antonio Aceti, Andrea Soricelli, Magdalena Viscione, Massimo Andreoni, Paolo M. Rossini, Alfredo Pennica

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: Treatment-naïve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-naïve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4.

Original language	English
Pages (from-to)	1792-1802
Number of pages	11
Journal	Clinical Neurophysiology
Volume	125
Issue number	9
DOIs	https://doi.org/10.1016/j.clinph.2014.01.024
Publication status	Published - 2014

Keywords

Alpha
Brain rhythms
CD4 lymphocyte
Human immunodeficiency virus (HIV)
Low-resolution brain electromagnetic source tomography (LORETA)
Resting-state electroencephalography (EEG)

ASJC Scopus subject areas

Clinical Neurology
Neurology
Physiology (medical)
Sensory Systems
Medicine(all)

Access to Document

10.1016/j.clinph.2014.01.024

Cite this

Babiloni, C., Buffo, P., Vecchio, F., Onorati, P., Muratori, C., Ferracuti, S., Roma, P., Battuello, M., Donato, N., Noce, G., Di Campli, F., Gianserra, L., Teti, E., Aceti, A., Soricelli, A., Viscione, M., Andreoni, M., Rossini, P. M., & Pennica, A. (2014). Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy. Clinical Neurophysiology, 125(9), 1792-1802. https://doi.org/10.1016/j.clinph.2014.01.024

Babiloni, C, Buffo, P, Vecchio, F, Onorati, P, Muratori, C, Ferracuti, S, Roma, P, Battuello, M, Donato, N, Noce, G, Di Campli, F, Gianserra, L, Teti, E, Aceti, A, Soricelli, A, Viscione, M, Andreoni, M, Rossini, PM & Pennica, A 2014, 'Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy', Clinical Neurophysiology, vol. 125, no. 9, pp. 1792-1802. https://doi.org/10.1016/j.clinph.2014.01.024

@article{3ce8d13864bc4d319e086c4ae8fcaf87,

title = "Cortical sources of resting-state EEG rhythms in {"}experienced{"} HIV subjects under antiretroviral therapy",

abstract = "Objective: Treatment-na{\"i}ve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-na{\"i}ve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4. ",

keywords = "Alpha, Brain rhythms, CD4 lymphocyte, Human immunodeficiency virus (HIV), Low-resolution brain electromagnetic source tomography (LORETA), Resting-state electroencephalography (EEG)",

author = "Claudio Babiloni and Paola Buffo and Fabrizio Vecchio and Paolo Onorati and Chiara Muratori and Stefano Ferracuti and Paolo Roma and Michele Battuello and Nicole Donato and Giuseppe Noce and {Di Campli}, Francesco and Laura Gianserra and Elisabetta Teti and Antonio Aceti and Andrea Soricelli and Magdalena Viscione and Massimo Andreoni and Rossini, {Paolo M.} and Alfredo Pennica",

year = "2014",

doi = "10.1016/j.clinph.2014.01.024",

language = "English",

volume = "125",

pages = "1792--1802",

journal = "Clinical Neurophysiology",

issn = "1388-2457",

publisher = "Elsevier Ireland Ltd",

number = "9",

}

TY - JOUR

T1 - Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy

AU - Babiloni, Claudio

AU - Buffo, Paola

AU - Vecchio, Fabrizio

AU - Onorati, Paolo

AU - Muratori, Chiara

AU - Ferracuti, Stefano

AU - Roma, Paolo

AU - Battuello, Michele

AU - Donato, Nicole

AU - Noce, Giuseppe

AU - Di Campli, Francesco

AU - Gianserra, Laura

AU - Teti, Elisabetta

AU - Aceti, Antonio

AU - Soricelli, Andrea

AU - Viscione, Magdalena

AU - Andreoni, Massimo

AU - Rossini, Paolo M.

AU - Pennica, Alfredo

PY - 2014

Y1 - 2014

N2 - Objective: Treatment-naïve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-naïve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4.

AB - Objective: Treatment-naïve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-naïve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4.

KW - Alpha

KW - Brain rhythms

KW - CD4 lymphocyte

KW - Human immunodeficiency virus (HIV)

KW - Low-resolution brain electromagnetic source tomography (LORETA)

KW - Resting-state electroencephalography (EEG)

UR - http://www.scopus.com/inward/record.url?scp=84906083187&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906083187&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2014.01.024

DO - 10.1016/j.clinph.2014.01.024

M3 - Article

C2 - 24631008

AN - SCOPUS:84906083187

VL - 125

SP - 1792

EP - 1802

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 9

ER -

Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this