TY - JOUR
T1 - Cortical sources of resting-state EEG rhythms in "experienced" HIV subjects under antiretroviral therapy
AU - Babiloni, Claudio
AU - Buffo, Paola
AU - Vecchio, Fabrizio
AU - Onorati, Paolo
AU - Muratori, Chiara
AU - Ferracuti, Stefano
AU - Roma, Paolo
AU - Battuello, Michele
AU - Donato, Nicole
AU - Noce, Giuseppe
AU - Di Campli, Francesco
AU - Gianserra, Laura
AU - Teti, Elisabetta
AU - Aceti, Antonio
AU - Soricelli, Andrea
AU - Viscione, Magdalena
AU - Andreoni, Massimo
AU - Rossini, Paolo M.
AU - Pennica, Alfredo
PY - 2014
Y1 - 2014
N2 - Objective: Treatment-naïve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-naïve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4.
AB - Objective: Treatment-naïve patients with human immunodeficiency virus (HIV) are characterized by diffuse abnormalities of resting-state cortical electroencephalographic (EEG) rhythms (Babiloni et al., 2012a). Here, we tested the hypothesis that these EEG rhythms vary as a function of the systemic immune activity and antiretroviral therapy (ART) in HIV patients. Methods: Resting-state eyes-closed EEG data were recorded in 68 ART-HIV patients (mini mental state evaluation (MMSE) of 27.5. ±. 0.3 SEM), in 60 treatment-naïve HIV subjects (MMSE of 27.5. ±. 0.4 SEM) and in 75 age-matched cognitively normal subjects (MMSE of 29.3. ±. 0.1 SEM). Based on the CD4 lymphocytes' count, we divided ART-HIV subjects into two subgroups: those with CD4. >. 500. cells/μl (ART-HIV+) and those with CD4.
KW - Alpha
KW - Brain rhythms
KW - CD4 lymphocyte
KW - Human immunodeficiency virus (HIV)
KW - Low-resolution brain electromagnetic source tomography (LORETA)
KW - Resting-state electroencephalography (EEG)
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U2 - 10.1016/j.clinph.2014.01.024
DO - 10.1016/j.clinph.2014.01.024
M3 - Article
C2 - 24631008
AN - SCOPUS:84906083187
VL - 125
SP - 1792
EP - 1802
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
SN - 1388-2457
IS - 9
ER -