Cortical sources of visual evoked potentials during consciousness of executive processes

Claudio Babiloni, Fabrizio Vecchio, Marco Iacoboni, Paola Buffo, Fabrizio Eusebi, Paolo Maria Rossini

Research output: Contribution to journalArticle

Abstract

What is the timing of cortical activation related to consciousness of visuo-spatial executive functions? Electroencephalographic data (128 channels) were recorded in 13 adults. Cue stimulus briefly appeared on right or left (equal probability) monitor side for a period, inducing about 50% of recognitions. It was then masked and followed (2 s) by a central visual go stimulus. Left (right) mouse button had to be clicked after right (left) cue stimulus. This "inverted" response indexed executive processes. Afterward, subjects said "seen" if they had detected the cue stimulus or "not seen" when it was missed. Sources of event-related potentials (ERPs) were estimated by LORETA software. The inverted responses were about 95% in seen trials and about 60% in not seen trials. Cue stimulus evoked frontal-parietooccipital potentials, having the same peak latencies in the seen and not seen data. Maximal difference in amplitude of the seen and not seen ERPs was detected at about 1300-ms post-stimulus (P3). P3 sources were higher in amplitude in the seen than not seen trials in dorsolateral prefrontal, premotor and parietooccipital areas. This was true in dorsolateral prefrontal and premotor cortex even when percentage of the inverted responses and reaction time were paired in the seen and not seen trials. These results suggest that, in normal subjects, the primary consciousness enhances the efficacy of visuo-spatial executive processes and is sub-served by a late (100- to 400-ms post-stimulus) enhancement of the neural synchronization in frontal areas.

Original languageEnglish
Pages (from-to)998-1013
Number of pages16
JournalHuman Brain Mapping
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 2009

Keywords

  • Awareness
  • Executive functions
  • Human cortex
  • LOR- ETA
  • Subliminal stimuli
  • Visual evoked potentials (VEPs)

ASJC Scopus subject areas

  • Clinical Neurology
  • Anatomy
  • Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Cortical sources of visual evoked potentials during consciousness of executive processes'. Together they form a unique fingerprint.

  • Cite this