Corticoresistant nephrotic syndrome associated with T-cell deficiency in two sisters

R. Tabin, J. P. Guignard, E. Gautier, M. Dubrit, M. Jeannet, J. Golaz, L. Moretta

Research output: Contribution to journalArticlepeer-review


The coexistence in two sisters, born to related parents, of a corticoresistant nephrotic syndrome, lymphopenia, an immune deficit, short stature and photophobia is described. The immune deficit is mainly cellular; studies of lymphocyte markers demonstrate a pronounced deficiency of T lymphocytes and Fc-μ receptor-bearing cells. It is suggested that a thorough examination of number and function of T cells should be performed in patients with a familial corticoresist nephrotic syndrome and recurrent infectious episodes before considering immunosuppressive treatment.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
Issue number1
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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