The coexistence in two sisters, born to related parents, of a corticoresistant nephrotic syndrome, lymphopenia, an immune deficit, short stature and photophobia is described. The immune deficit is mainly cellular; studies of lymphocyte markers demonstrate a pronounced deficiency of T lymphocytes and Fc-μ receptor-bearing cells. It is suggested that a thorough examination of number and function of T cells should be performed in patients with a familial corticoresist nephrotic syndrome and recurrent infectious episodes before considering immunosuppressive treatment.
|Number of pages||4|
|Publication status||Published - 1983|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health