Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma

G. Pellacani, A. Witkowski, A. M. Cesinaro, A. Losi, G. L. Colombo, A. Campagna, C. Longo, S. Piana, N. De Carvalho, F. Giusti, F. Farnetani

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background The sub-optimal diagnostic accuracy for melanoma leads to excise a high number of benign lesions, with consequent costs. Reflectance confocal microscopy (RCM) improves diagnostic specificity, thus possibly inducing a reduction in unnecessary excisions and related costs. Objective To estimate the influence of RCM on number of benign lesions needed to excise (NNE) a melanoma, in term of clinical outcomes and costs per patient. Patients and Methods Skin neoplasms excised by the dermatology public service in the Province of Modena were retrieved form centralized pathology database. Differences in NNE between the territorial service (using dermoscopy only) and the University Hospital (adding also RCM to the patients' workflow) were calculated and cost analysis was performed through a micro-costing approach. Results A large reduction in benign lesions excised at University Hospital was evident, leading to NNE of 6.25 for University Hospital, compared to 19.41 for Territorial Dermatology. Since 4320 unnecessary excisions can be saved every million inhabitants, an overall yearly saving of over 280,000 Eur can be expected from the use of RCM. Conclusions The systematic use of RCM was dramatically affecting the number of benign lesions excised, and this can be translated in a significant cost-benefit advantage.

Original languageEnglish
Pages (from-to)413-419
Number of pages7
JournalJournal of the European Academy of Dermatology and Venereology
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 1 2016

Fingerprint

Confocal Microscopy
Cost-Benefit Analysis
Melanoma
Costs and Cost Analysis
Dermatology
Dermoscopy
Workflow
Skin Neoplasms
Databases
Pathology

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

Cite this

Pellacani, G., Witkowski, A., Cesinaro, A. M., Losi, A., Colombo, G. L., Campagna, A., ... Farnetani, F. (2016). Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma. Journal of the European Academy of Dermatology and Venereology, 30(3), 413-419. https://doi.org/10.1111/jdv.13408

Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma. / Pellacani, G.; Witkowski, A.; Cesinaro, A. M.; Losi, A.; Colombo, G. L.; Campagna, A.; Longo, C.; Piana, S.; De Carvalho, N.; Giusti, F.; Farnetani, F.

In: Journal of the European Academy of Dermatology and Venereology, Vol. 30, No. 3, 01.03.2016, p. 413-419.

Research output: Contribution to journalArticle

Pellacani, G, Witkowski, A, Cesinaro, AM, Losi, A, Colombo, GL, Campagna, A, Longo, C, Piana, S, De Carvalho, N, Giusti, F & Farnetani, F 2016, 'Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma', Journal of the European Academy of Dermatology and Venereology, vol. 30, no. 3, pp. 413-419. https://doi.org/10.1111/jdv.13408
Pellacani, G. ; Witkowski, A. ; Cesinaro, A. M. ; Losi, A. ; Colombo, G. L. ; Campagna, A. ; Longo, C. ; Piana, S. ; De Carvalho, N. ; Giusti, F. ; Farnetani, F. / Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma. In: Journal of the European Academy of Dermatology and Venereology. 2016 ; Vol. 30, No. 3. pp. 413-419.
@article{f52d3116d81a4e2799b918ca396708e5,
title = "Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma",
abstract = "Background The sub-optimal diagnostic accuracy for melanoma leads to excise a high number of benign lesions, with consequent costs. Reflectance confocal microscopy (RCM) improves diagnostic specificity, thus possibly inducing a reduction in unnecessary excisions and related costs. Objective To estimate the influence of RCM on number of benign lesions needed to excise (NNE) a melanoma, in term of clinical outcomes and costs per patient. Patients and Methods Skin neoplasms excised by the dermatology public service in the Province of Modena were retrieved form centralized pathology database. Differences in NNE between the territorial service (using dermoscopy only) and the University Hospital (adding also RCM to the patients' workflow) were calculated and cost analysis was performed through a micro-costing approach. Results A large reduction in benign lesions excised at University Hospital was evident, leading to NNE of 6.25 for University Hospital, compared to 19.41 for Territorial Dermatology. Since 4320 unnecessary excisions can be saved every million inhabitants, an overall yearly saving of over 280,000 Eur can be expected from the use of RCM. Conclusions The systematic use of RCM was dramatically affecting the number of benign lesions excised, and this can be translated in a significant cost-benefit advantage.",
author = "G. Pellacani and A. Witkowski and Cesinaro, {A. M.} and A. Losi and Colombo, {G. L.} and A. Campagna and C. Longo and S. Piana and {De Carvalho}, N. and F. Giusti and F. Farnetani",
year = "2016",
month = "3",
day = "1",
doi = "10.1111/jdv.13408",
language = "English",
volume = "30",
pages = "413--419",
journal = "Journal of the European Academy of Dermatology and Venereology",
issn = "0926-9959",
publisher = "wiley",
number = "3",

}

TY - JOUR

T1 - Cost-benefit of reflectance confocal microscopy in the diagnostic performance of melanoma

AU - Pellacani, G.

AU - Witkowski, A.

AU - Cesinaro, A. M.

AU - Losi, A.

AU - Colombo, G. L.

AU - Campagna, A.

AU - Longo, C.

AU - Piana, S.

AU - De Carvalho, N.

AU - Giusti, F.

AU - Farnetani, F.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Background The sub-optimal diagnostic accuracy for melanoma leads to excise a high number of benign lesions, with consequent costs. Reflectance confocal microscopy (RCM) improves diagnostic specificity, thus possibly inducing a reduction in unnecessary excisions and related costs. Objective To estimate the influence of RCM on number of benign lesions needed to excise (NNE) a melanoma, in term of clinical outcomes and costs per patient. Patients and Methods Skin neoplasms excised by the dermatology public service in the Province of Modena were retrieved form centralized pathology database. Differences in NNE between the territorial service (using dermoscopy only) and the University Hospital (adding also RCM to the patients' workflow) were calculated and cost analysis was performed through a micro-costing approach. Results A large reduction in benign lesions excised at University Hospital was evident, leading to NNE of 6.25 for University Hospital, compared to 19.41 for Territorial Dermatology. Since 4320 unnecessary excisions can be saved every million inhabitants, an overall yearly saving of over 280,000 Eur can be expected from the use of RCM. Conclusions The systematic use of RCM was dramatically affecting the number of benign lesions excised, and this can be translated in a significant cost-benefit advantage.

AB - Background The sub-optimal diagnostic accuracy for melanoma leads to excise a high number of benign lesions, with consequent costs. Reflectance confocal microscopy (RCM) improves diagnostic specificity, thus possibly inducing a reduction in unnecessary excisions and related costs. Objective To estimate the influence of RCM on number of benign lesions needed to excise (NNE) a melanoma, in term of clinical outcomes and costs per patient. Patients and Methods Skin neoplasms excised by the dermatology public service in the Province of Modena were retrieved form centralized pathology database. Differences in NNE between the territorial service (using dermoscopy only) and the University Hospital (adding also RCM to the patients' workflow) were calculated and cost analysis was performed through a micro-costing approach. Results A large reduction in benign lesions excised at University Hospital was evident, leading to NNE of 6.25 for University Hospital, compared to 19.41 for Territorial Dermatology. Since 4320 unnecessary excisions can be saved every million inhabitants, an overall yearly saving of over 280,000 Eur can be expected from the use of RCM. Conclusions The systematic use of RCM was dramatically affecting the number of benign lesions excised, and this can be translated in a significant cost-benefit advantage.

UR - http://www.scopus.com/inward/record.url?scp=84959206341&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959206341&partnerID=8YFLogxK

U2 - 10.1111/jdv.13408

DO - 10.1111/jdv.13408

M3 - Article

AN - SCOPUS:84959206341

VL - 30

SP - 413

EP - 419

JO - Journal of the European Academy of Dermatology and Venereology

JF - Journal of the European Academy of Dermatology and Venereology

SN - 0926-9959

IS - 3

ER -