Cost-effectiveness analysis for trigeminal neuralgia: Cyberknife vs microvascular decompression

Rossana Tarricone, Giovanni Aguzzi, Francesco Musi, Laura Fariselli, Andrea Casasco

Research output: Contribution to journalArticlepeer-review


Background/Aims: We present the preliminary results of a cost-effectiveness analysis of cyberknife radiosurgery (CKR) versus microvascular decompression (MVD) for patients with medically unresponsive trigeminal neuralgia. Methods: Direct healthcare costs from hospital's perspective attributable to CKR and MVD were collected. Pain level caused by trigeminal neuralgia was measured through the Barrow Neurological Institute pain intensity scoring criteria, at admission and after an average of 6 months follow-up. Results: 20 patients for both arms were enrolled, for a total of 40 patients. The two procedures resulted equally effective at 6 month follow-up, with different resources consumption: CKR reducing hospital costs by an average of 34% per patient. The robustness of these results was confirmed in appropriate sensitivity analyses. Conclusion: CKR resulted to be a cost-saving alternative compared with the surgical intervention.

Original languageEnglish
Pages (from-to)647-652
Number of pages6
JournalNeuropsychiatric Disease and Treatment
Issue number3
Publication statusPublished - 2008


  • Cost-effectiveness analysis
  • Cyberknife
  • Decision making
  • Microvascular decompression
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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