TY - JOUR
T1 - Cost-effectiveness analysis of tuberculosis control policies in Ivanovo Oblast, Russian federation
AU - Migliori, G. B.
AU - Khomenko, A. G.
AU - Punga, V. V.
AU - Ambrosetti, M.
AU - Danilova, I.
AU - Ribka, L. N.
AU - Grzemska, M.
AU - Sawert, H.
AU - Raviglione, M. C.
PY - 1998
Y1 - 1998
N2 - Many of the current tuberculosis control programmes in the Russian Federation are based on costly strategies which are underfunded and use long, individualized treatment regimens. This article compares, using a cost- effectiveness analysis, the new WHO strategy implemented in the Ivanovo Oblast (case-finding among symptomatic patients (SCF) and shorter regimens) and the old strategy (active screening of the asymptomatic population (ACF) and longer regimens). The cost per case cured was calculated at different levels of cure rate (45-95%) using three scenarios to describe the new WHO strategy (use of WHO-recommended regimens and three options at increasing rates of admission) and a fourth scenario to describe the old strategy (all patients admitted for the whole treatment and longer regimens). The cost per case detected was determined by calculating the following: yield of the new and old strategy (number of examinations necessary to diagnose one case); cost of the diagnostic process; multiplying yield per cost according to the three scenarios describing the new WHO strategy and a fourth scenario describing the old strategy. In the Ivanovo Oblast the cost per case cured, at 85% cure rate level, ranged from USS 1197 (new strategy, scenario 1 without food) to USS 6293 (old strategy, scenario 4) the cost per case detected ranged from USS 1581 (new strategy, scenario 1) to USS 4000 (old strategy, scenario 4). Significant savings can result from shifting towards the new WHO strategy. Decision-makers and health administrators should be responsible for re-investing the financial and human resources mobilized by the adoption of cost-effective strategies within the TB control programme.
AB - Many of the current tuberculosis control programmes in the Russian Federation are based on costly strategies which are underfunded and use long, individualized treatment regimens. This article compares, using a cost- effectiveness analysis, the new WHO strategy implemented in the Ivanovo Oblast (case-finding among symptomatic patients (SCF) and shorter regimens) and the old strategy (active screening of the asymptomatic population (ACF) and longer regimens). The cost per case cured was calculated at different levels of cure rate (45-95%) using three scenarios to describe the new WHO strategy (use of WHO-recommended regimens and three options at increasing rates of admission) and a fourth scenario to describe the old strategy (all patients admitted for the whole treatment and longer regimens). The cost per case detected was determined by calculating the following: yield of the new and old strategy (number of examinations necessary to diagnose one case); cost of the diagnostic process; multiplying yield per cost according to the three scenarios describing the new WHO strategy and a fourth scenario describing the old strategy. In the Ivanovo Oblast the cost per case cured, at 85% cure rate level, ranged from USS 1197 (new strategy, scenario 1 without food) to USS 6293 (old strategy, scenario 4) the cost per case detected ranged from USS 1581 (new strategy, scenario 1) to USS 4000 (old strategy, scenario 4). Significant savings can result from shifting towards the new WHO strategy. Decision-makers and health administrators should be responsible for re-investing the financial and human resources mobilized by the adoption of cost-effective strategies within the TB control programme.
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M3 - Article
C2 - 9868838
AN - SCOPUS:0032432091
VL - 76
SP - 475
EP - 483
JO - Bulletin of the World Health Organization
JF - Bulletin of the World Health Organization
SN - 0043-9686
IS - 5
ER -