TY - JOUR
T1 - COVID-19 and kidney transplantation: an Italian Survey and Consensus
T2 - Journal of Nephrology
AU - Vistoli, F.
AU - Furian, L.
AU - Maggiore, U.
AU - Caldara, R.
AU - Cantaluppi, V.
AU - Ferraresso, M.
AU - Zaza, G.
AU - Cardillo, M.
AU - Biancofiore, G.
AU - Menichetti, F.
AU - Russo, A.
AU - Turillazzi, E.
AU - Di Paolo, M.
AU - Grandaliano, G.
AU - Boggi, U.
AU - Brunori, G.
AU - Petrini, F.
AU - Valenza, F.
AU - Lavezzo, B.
AU - Bonucchi, D.
AU - Capocasale, E.
AU - Grossi, P.
AU - Ponticelli, C.
AU - Sandrini, S.
AU - Schena, F.P.
AU - Segoloni, G.
AU - Biancone, L.
AU - Boschiero, L.
AU - Rigotti, P.
AU - Comai, G.
AU - Bossini, N.
AU - Minetti, E.
AU - Iaria, G.
AU - Ambrosini, A.
AU - Messa, P.G.
AU - Boscutti, G.
AU - Carmellini, M.
AU - Caputo, F.
AU - Ranghino, A.
AU - De Rosa, P.
AU - Federico, S.
AU - Veroux, M.
AU - Cirami, C.
AU - Nordio, M.
AU - Citterio, F.
AU - Piredda, G.B.
AU - Pretagostini, R.
AU - De Paolis, P.
AU - Rampino, T.
AU - Pisani, F.
AU - Cappelli, G.
AU - Secchi, A.
AU - Salis, P.
AU - Gastaldon, F.
AU - Mallamaci, F.
AU - Strologo, L.D.
AU - Taglioni, C.
AU - Teresa, P.
AU - Peruzzi, L.
AU - Gesualdo, L.
AU - Gotti, E.
AU - Feltracco, P.
AU - Paoletti, E.
AU - Network, on behalf of the Italian National Kidney Transplantation
AU - Nephrology, the Joint Committee of the Italian Society of Organ Transplantation and the Italian Society of
N1 - Cited By :7
Export Date: 11 March 2021
CODEN: JLNEE
Correspondence Address: Zaza, G.; Renal Unit, Italy; email: gianluigi.zaza@univr.i
Chemicals/CAS: azathioprine, 446-86-6; methylprednisolone, 6923-42-8, 83-43-2; mycophenolate mofetil, 116680-01-4, 128794-94-5; tocilizumab, 375823-41-9
PY - 2020
Y1 - 2020
N2 - Italy was the first Western country to face the COVID-19 pandemic. Here we report the results of a national survey on kidney transplantation activity in February and March 2020, and the results of a three-round Delphi consensus promoted by four scientific societies: the Italian Society of Organ Transplantation, the Italian Society of Nephrology, the Italian Society of Anesthesia and Intensive Care, and the Italian Group on Antimicrobial Stewardship. All 41 Italian transplant centers were invited to express their opinion in the Delphi rounds along with a group of seven experts. The survey revealed that, starting from March 2020, there was a decline in kidney transplantation activity in Italy, especially for living-related transplants. Overall, 60 recipients tested positive for SARS-CoV2 infection, 57 required hospitalization, 17 were admitted to the ICU, and 11 died. The online consensus had high response rates at each round (95.8%, 95.8%, and 89.5%, respectively). Eventually, 27 of 31 proposed statements were approved (87.1%), 12 at the first or second round (38.7%), and 3 at the third (9.7%). Based on the Italian experience, we discuss the reasons for the changes in kidney transplantation activity during the COVID-19 pandemic in Western countries. We also provide working recommendations for the organization and management of kidney transplantation under these conditions. © 2020, Italian Society of Nephrology.
AB - Italy was the first Western country to face the COVID-19 pandemic. Here we report the results of a national survey on kidney transplantation activity in February and March 2020, and the results of a three-round Delphi consensus promoted by four scientific societies: the Italian Society of Organ Transplantation, the Italian Society of Nephrology, the Italian Society of Anesthesia and Intensive Care, and the Italian Group on Antimicrobial Stewardship. All 41 Italian transplant centers were invited to express their opinion in the Delphi rounds along with a group of seven experts. The survey revealed that, starting from March 2020, there was a decline in kidney transplantation activity in Italy, especially for living-related transplants. Overall, 60 recipients tested positive for SARS-CoV2 infection, 57 required hospitalization, 17 were admitted to the ICU, and 11 died. The online consensus had high response rates at each round (95.8%, 95.8%, and 89.5%, respectively). Eventually, 27 of 31 proposed statements were approved (87.1%), 12 at the first or second round (38.7%), and 3 at the third (9.7%). Based on the Italian experience, we discuss the reasons for the changes in kidney transplantation activity during the COVID-19 pandemic in Western countries. We also provide working recommendations for the organization and management of kidney transplantation under these conditions. © 2020, Italian Society of Nephrology.
KW - Consensus
KW - COVID-19
KW - Kidney transplantation
KW - Survey
KW - azathioprine
KW - methylprednisolone
KW - mycophenolate mofetil
KW - tocilizumab
KW - adult respiratory distress syndrome
KW - antihypertensive therapy
KW - antimicrobial stewardship
KW - antiviral therapy
KW - Article
KW - artificial ventilation
KW - coronavirus disease 2019
KW - follow up
KW - health care personnel
KW - health survey
KW - hospitalization
KW - human
KW - immunosuppressive treatment
KW - intensive care unit
KW - Italian (citizen)
KW - kidney graft
KW - kidney transplantation
KW - pandemic
KW - prevalence
KW - public health
KW - questionnaire
KW - reverse transcription polymerase chain reaction
KW - Severe acute respiratory syndrome coronavirus 2
KW - telemedicine
KW - virus pneumonia
KW - Betacoronavirus
KW - Coronavirus infection
KW - living donor
KW - Coronavirus Infections
KW - Humans
KW - Kidney Transplantation
KW - Living Donors
KW - Pandemics
KW - Pneumonia, Viral
U2 - 10.1007/s40620-020-00755-8
DO - 10.1007/s40620-020-00755-8
M3 - Article
VL - 33
SP - 667
EP - 680
JO - J. Nephrol.
JF - J. Nephrol.
SN - 1121-8428
IS - 4
ER -