COVID-19 and Oral Surgery: A narrative review of preoperative mouth rinses

Tiziano Testori, Hom Lay Wang, Matteo Basso, Giordano Bordini, Arturo Dian, Carlo Vitelli, Ivana Miletic, Massimo Del Fabbro

Research output: Contribution to journalReview articlepeer-review


Objective: To provide a narrative review of the preprocedural mouth rinse protocols suggested for oral surgery in order to contrast the presence of SARS-CoV-2 in aerosol. Sources and Methods: Electronic searches were performed in medical databases PubMed, Medline, CINAHN and Scopus to identify relevant studies published up until the third week of April 2020. This research was supplemented by exploration through a web-based search engine as well as a manual search for international and national guidelines. Studies and protocols which suggested preoperative mouth rinsing as a recommended measure during the COVID-19 outbreak were included. Given the small number of studies, a narrative literature review was conducted. In total, 15 references (11 articles and 4 guidelines) were considered relevant and were critically analysed. Conclusion: The findings show a high heterogeneity in the protocols suggested. Further research is required to better understand the viral features and epidemiologic characteristics of this new virus and to test the efficacy of commonly used antiseptics against SARS-CoV-2 in future clinical trials. However, the use of chlorhexidine, hydrogen peroxide, PVP-I and cetylpyridinium chloride in contrasting the spread of Covid-19 is described as advisable and substantial in different publications.

Original languageEnglish
Pages (from-to)431-441
Number of pages11
JournalActa Stomatologica Croatica
Issue number4
Publication statusPublished - 2021


  • Clinical Protocols
  • Local Anti-Infective Agents
  • Mouthwashes
  • Occupational Exposure
  • SARS Virus

ASJC Scopus subject areas

  • Dentistry(all)


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