Covid-19 and the role of smoking: the protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly)

Maria Sofia Cattaruzza, Giuseppe Gorini, Cristina Bosetti, Roberto Boffi, Alessandra Lugo, Chiara Veronese, Giulia Carreras, Claudia Santucci, Chiara Stival, Roberta Pacifici, Vincenzo Zagà, Silvano Gallus, Federico Giulietti, Riccardo Sarzani, Francesco Spannella, Mario Del Donno, Stefania Tartaglione, Giuseppina Marrazzo, Girolamo Pelaia, Vincenzo D'AgostoAlice Berti, Fabio Voller, Salvatore Cardellicchio, Chiara Cresci, Maria Pia Foschino Barbaro, Raffaele De Palma, Simone Negrini, Vera Sicbaldi, Antonella Serafini, Mario Bisconti, Leonida Refolo, Giovanni Landoni, Patrizia Rovere, Giulia Veronesi, Paola Faverio, Werner Garavello, Alberto Pesci, Raffaella Giacobbe, Paola Martucci, Roberto Parrella, Francesco Scarano, Marina Aiello, Alfredo Chetta, Cosimo Franco, Angelo Mangia, Laura Carrozzi, Fabrizio Maggi, Fabio Monzani, Francesco Pistelli, Patrizia Russo, Antonio Sanna, Filippo Maria Barreca, Valentina Conti, Enrico Rossi, Mei Ruli, Silvana Ruli, Shokoofe Eslami Varzaneh, Rosastella Principe, Simone Guerrini, Alfredo Sebastiani, Giovanni Galluccio, Aldo Pezzuto, Alberto Ricci, Elena Casali, Claudio Mastroianni, Pietro Pirina, Francesca Polo, Fabio Beatrice, Micaela Romagnoli, Massimo Baraldo, Pier Giorgio Cojutti, Carlo Tascini, Davide Pecori, Elena Graziano, Biagio Tinghino

Research output: Contribution to journalArticlepeer-review

Abstract

The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role of tobacco smoking and other lifestyle habits on COVID-19 severity and progression, we designed a longitudinal observational study titled COvid19 and SMOking in ITaly (COSMO-IT). About 30 Italian hospitals in North, Centre and South of Italy joined the study. Its main aims are: 1) to quantify the role of tobacco smoking and smoking cessation on the severity and progression of COVID-19 in hospitalized patients; 2) to compare smoking prevalence and severity of the disease in relation to smoking in hospitalized COVID-19 patients versus patients treated at home; 3) to quantify the association between other lifestyle factors, such as e-cigarette and HTP use, alcohol and obesity and the risk of unfavourable COVID-19 outcomes. Socio-demographic, lifestyle and medical history information will be gathered for around 3000 hospitalized and 700-1000 home-isolated, laboratory-confirmed, COVID-19 patients. Given the current absence of a vaccine against SARS-COV-2 and the lack of a specific treatment for -COVID-19, prevention strategies are of extreme importance. This project, designed to highly contribute to the international scientific debate on the role of avoidable lifestyle habits on COVID-19 severity, will provide valuable epidemiological data in order to support important recommendations to prevent COVID-19 incidence, progression and mortality.

Original languageEnglish
Pages (from-to)e2020062
JournalActa Biomed
Volume91
Issue number3
DOIs
Publication statusPublished - Aug 27 2020

Keywords

  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections/epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Italy/epidemiology
  • Life Style
  • Male
  • Pandemics
  • Pneumonia, Viral/epidemiology
  • Prevalence
  • Prospective Studies
  • SARS-CoV-2
  • Tobacco Smoking/adverse effects

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