Cranial sutures: A multidisciplinary review

Antonio Di Ieva, Emiliano Bruner, Jennilee Davidson, Patrizia Pisano, Thomas Haider, Scellig S. Stone, Michael D. Cusimano, Manfred Tschabitscher, Fabio Grizzi

Research output: Contribution to journalArticle

Abstract

Introduction: Progress in cranial suture research is shaping our current understanding of the topic; however, emphasis has been placed on individual contributing components rather than the cranial sutural system as a whole. Improving our holistic view helps further guide clinicians who treat cranial sutural abnormalities as well as researchers who study them. Materials and methods: Information from anatomy, anthropology, surgery, and computed modeling was integrated to provide a perspective to interpret suture formation and variability within the cranial functional and structural system. Results: Evidence from experimental settings, simulations, and evolution suggest a multifactorial morphogenetic process associated with functions and morphology of the sutures. Despite molecular influences, the biomechanical cranial environment has a main role in both the ontogenetic and phylogenetic suture dynamics. Conclusions: Furthering our holistic understanding of the intricate cranial sutural system promises to expand our knowledge and enhance our ability to treat associated anomalies.

Original languageEnglish
Pages (from-to)893-905
Number of pages13
JournalChild's Nervous System
Volume29
Issue number6
DOIs
Publication statusPublished - Jun 2013

Keywords

  • Braincase
  • Cranial anatomy
  • Craniosynostosis
  • Fractal geometry
  • Functional craniology
  • Sutures

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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