Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

Monica Fumagalli, Luca Antonio Ramenghi, Agnese De Carli, Laura Bassi, Pietro Farè, Francesca Dessimone, Silvia Pisoni, Ida Sirgiovanni, Michela Groppo, Alessandra Ometto, Dario Consonni, Fabio Triulzi, Fabio Mosca

Research output: Contribution to journalArticlepeer-review


Background: Late preterm infants are the most represented premature babies. They are exposed to a wide spectrum of brain lesions which are often clinically silent, supporting a possible role of cerebral ultrasound screening. Aim of the study is to describe the pattern of cranial ultrasound abnormalities in late preterm infants and to define the need for cranial ultrasound according to perinatal risk factors. Methods: A hospital-based cranial ultrasound screening was carried out by performing two scans (at 1 and 5 weeks). Unfavorable cranial ultrasound at 5 weeks was defined as either persistent periventricular hyperechogenicity or severe abnormalities. Results: One thousand one hundred seventy-two infants were included. Periventricular hyperechogenicity and severe abnormalities were observed in, respectively, 19.6 % and 1 % of late preterms at birth versus 1.8 % and 1.4 % at 5 weeks. Periventricular hyperechogenicity resolved in 91.3 %. At the univariate analysis gestational age (OR 0.5, 95 % CI 0.32-0.77), Apgar score

Original languageEnglish
Article number172
JournalItalian Journal of Pediatrics
Issue number1
Publication statusPublished - Sep 24 2015


  • Brain injury
  • Cranial ultrasound
  • Late preterm infant
  • Perinatal risk factors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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