CRH-R1 mRNA expression in two strains of inbred mice and its regulation after repeated restraint stress

Luciana Giardino, Stefano Puglisi-Allegra, Sandra Ceccatelli

Research output: Contribution to journalArticlepeer-review

Abstract

Using in-situ hybridization histochemistry we investigated the distribution of CRH receptor 1 (CRH-R1) mRNA in the cortex of C57BL/6 (C57) and DBA/2 (DBA) strains and its regulation after repeated restraint stress. We show that DBA mice have a higher concentration of CRH-R1 mRNA than C57 mice. Repeated restraint stress produced an increase in CRH-R1 mRNA expression of C57 mice, whereas it was uneffective in DBA mice.

Original languageEnglish
Pages (from-to)310-314
Number of pages5
JournalMolecular Brain Research
Volume40
Issue number2
DOIs
Publication statusPublished - Sep 1 1996

Keywords

  • C57
  • Cortical areas
  • CRH-R1 mRNA
  • DBA
  • In-situ hybridization
  • Restraint stress

ASJC Scopus subject areas

  • Molecular Biology
  • Cellular and Molecular Neuroscience

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