Critical choices for modeling breast cancer in transgenic mouse models

Isabella Caligiuri, Flavio Rizzolio, Silvia Boffo, Antonio Giordano, Giuseppe Toffoli

Research output: Contribution to journalArticlepeer-review


Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken into account when the mouse is used, with special emphasis on transgenic models.

Original languageEnglish
Pages (from-to)2988-2991
Number of pages4
JournalJournal of Cellular Physiology
Issue number8
Publication statusPublished - Aug 2012

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology


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