Cross-reactivity of Fusarium spp. in the Aspergillus galactomannan enzyme-linked immunosorbent assay

Anna Maria Tortorano, Maria Carmela Esposto, Anna Prigitano, Anna Grancini, Cristina Ossi, Caterina Cavanna, Giuliana Lo Cascio

Research output: Contribution to journalArticlepeer-review

Abstract

Nine of 11 hematological patients with disseminated/deep-seated Fusarium infection tested at least twice for Aspergillus galactomannan (GM) had repeated positive results in the absence of Aspergillus isolation in culture. The centrifuged supernatants of 12 Fusarium isolates were tested by a GM enzyme-linked immunosorbent assay (EIA). All the isolates produced positive reactions when tested undiluted. These results show cross-reactivity of Fusarium spp. with Aspergillus GM that may constitute a drawback with respect to the specificity of the Platelia EIA.

Original languageEnglish
Pages (from-to)1051-1053
Number of pages3
JournalJournal of Clinical Microbiology
Volume50
Issue number3
DOIs
Publication statusPublished - Mar 2012

ASJC Scopus subject areas

  • Microbiology (medical)

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