Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings

Maria Rita Parisi, Laura Soldini, Gianmarino Vidoni, Felice Clemente, Chiara Mabellini, Teresa Belloni, Silvia Nozza, Livia Brignolo, Silvia Negri, Stefano Rusconi, Karin Schlusnus, Fernanda Dorigatti, Adriano Lazzarin

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The submerged portion of undiagnosed HIV infection in Italy is about 30% of subjects found seropositive. This fact represents one of the most important public health problems hindering the control of infection progression. This means we need to fight unawareness and social stigma and promote easy and friendly access to HIV test. We developed a Prevention Program called "EASY test Project", offering a new rapid HIV test on oral fluid, to evaluate the acceptability of an alternative, free and anonymous test available in different settings (on board a "Motor Home" at public events, Points of Care, STDs outpatient prevention units and GP surgeries). From December 2008 to December 2012 we performed 7,865 HIV saliva tests, with 50 new infections found (0.6% of the total) out of 140,000 informed subjects. From the self-reported characteristics of respondents, the population approaching the EAST test project was represented by males (70%) aged between 20 and 50 years, 61% with a medium-high education level, 62% homosexuals (MSM), 88% reported unsafe sexual behaviours, and 48% had never undergone an HIV screening test. In five years of the Prevention Program, 100% of subjects interviewed gave a general favorable consent in approaching rapid and not invasive screening, immediate return of the result, and a timely specialized approach and treatment of HIV positive subjects. Results from our study confirm that the rapid and alternative test may contribute to HIV prevention strategies and to the control of the spread of infection and HIV disease progression by reaching a larger population, particularly when and where regular screening procedures are difficult to obtain or are not preferred.

Original languageEnglish
Pages (from-to)121-132
Number of pages12
JournalNew Microbiologica
Volume36
Issue number2
Publication statusPublished - Apr 2013

Fingerprint

HIV-2
HIV Infections
HIV-1
Cross-Sectional Studies
HIV
Infection Control
Point-of-Care Systems
Social Stigma
Population Characteristics
Sexually Transmitted Diseases
Saliva
Sexual Behavior
Italy
Disease Progression
Outpatients
Public Health
Education
Infection
Population

Keywords

  • HIV positive submerged people
  • HIV prevention
  • HIV screening test
  • Late HIV diagnosis
  • Saliva/oral fluid test

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Parisi, M. R., Soldini, L., Vidoni, G., Clemente, F., Mabellini, C., Belloni, T., ... Lazzarin, A. (2013). Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings. New Microbiologica, 36(2), 121-132.

Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings. / Parisi, Maria Rita; Soldini, Laura; Vidoni, Gianmarino; Clemente, Felice; Mabellini, Chiara; Belloni, Teresa; Nozza, Silvia; Brignolo, Livia; Negri, Silvia; Rusconi, Stefano; Schlusnus, Karin; Dorigatti, Fernanda; Lazzarin, Adriano.

In: New Microbiologica, Vol. 36, No. 2, 04.2013, p. 121-132.

Research output: Contribution to journalArticle

Parisi, MR, Soldini, L, Vidoni, G, Clemente, F, Mabellini, C, Belloni, T, Nozza, S, Brignolo, L, Negri, S, Rusconi, S, Schlusnus, K, Dorigatti, F & Lazzarin, A 2013, 'Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings', New Microbiologica, vol. 36, no. 2, pp. 121-132.
Parisi, Maria Rita ; Soldini, Laura ; Vidoni, Gianmarino ; Clemente, Felice ; Mabellini, Chiara ; Belloni, Teresa ; Nozza, Silvia ; Brignolo, Livia ; Negri, Silvia ; Rusconi, Stefano ; Schlusnus, Karin ; Dorigatti, Fernanda ; Lazzarin, Adriano. / Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings. In: New Microbiologica. 2013 ; Vol. 36, No. 2. pp. 121-132.
@article{38253c6973394586b0e5862abce54ea3,
title = "Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings",
abstract = "The submerged portion of undiagnosed HIV infection in Italy is about 30{\%} of subjects found seropositive. This fact represents one of the most important public health problems hindering the control of infection progression. This means we need to fight unawareness and social stigma and promote easy and friendly access to HIV test. We developed a Prevention Program called {"}EASY test Project{"}, offering a new rapid HIV test on oral fluid, to evaluate the acceptability of an alternative, free and anonymous test available in different settings (on board a {"}Motor Home{"} at public events, Points of Care, STDs outpatient prevention units and GP surgeries). From December 2008 to December 2012 we performed 7,865 HIV saliva tests, with 50 new infections found (0.6{\%} of the total) out of 140,000 informed subjects. From the self-reported characteristics of respondents, the population approaching the EAST test project was represented by males (70{\%}) aged between 20 and 50 years, 61{\%} with a medium-high education level, 62{\%} homosexuals (MSM), 88{\%} reported unsafe sexual behaviours, and 48{\%} had never undergone an HIV screening test. In five years of the Prevention Program, 100{\%} of subjects interviewed gave a general favorable consent in approaching rapid and not invasive screening, immediate return of the result, and a timely specialized approach and treatment of HIV positive subjects. Results from our study confirm that the rapid and alternative test may contribute to HIV prevention strategies and to the control of the spread of infection and HIV disease progression by reaching a larger population, particularly when and where regular screening procedures are difficult to obtain or are not preferred.",
keywords = "HIV positive submerged people, HIV prevention, HIV screening test, Late HIV diagnosis, Saliva/oral fluid test",
author = "Parisi, {Maria Rita} and Laura Soldini and Gianmarino Vidoni and Felice Clemente and Chiara Mabellini and Teresa Belloni and Silvia Nozza and Livia Brignolo and Silvia Negri and Stefano Rusconi and Karin Schlusnus and Fernanda Dorigatti and Adriano Lazzarin",
year = "2013",
month = "4",
language = "English",
volume = "36",
pages = "121--132",
journal = "New Microbiologica",
issn = "1121-7138",
publisher = "Luigi Ponzio e figlio Editori",
number = "2",

}

TY - JOUR

T1 - Cross-sectional study of community serostatus to highlight undiagnosed HIV infections with oral fluid HIV-1/2 rapid test in non-conventional settings

AU - Parisi, Maria Rita

AU - Soldini, Laura

AU - Vidoni, Gianmarino

AU - Clemente, Felice

AU - Mabellini, Chiara

AU - Belloni, Teresa

AU - Nozza, Silvia

AU - Brignolo, Livia

AU - Negri, Silvia

AU - Rusconi, Stefano

AU - Schlusnus, Karin

AU - Dorigatti, Fernanda

AU - Lazzarin, Adriano

PY - 2013/4

Y1 - 2013/4

N2 - The submerged portion of undiagnosed HIV infection in Italy is about 30% of subjects found seropositive. This fact represents one of the most important public health problems hindering the control of infection progression. This means we need to fight unawareness and social stigma and promote easy and friendly access to HIV test. We developed a Prevention Program called "EASY test Project", offering a new rapid HIV test on oral fluid, to evaluate the acceptability of an alternative, free and anonymous test available in different settings (on board a "Motor Home" at public events, Points of Care, STDs outpatient prevention units and GP surgeries). From December 2008 to December 2012 we performed 7,865 HIV saliva tests, with 50 new infections found (0.6% of the total) out of 140,000 informed subjects. From the self-reported characteristics of respondents, the population approaching the EAST test project was represented by males (70%) aged between 20 and 50 years, 61% with a medium-high education level, 62% homosexuals (MSM), 88% reported unsafe sexual behaviours, and 48% had never undergone an HIV screening test. In five years of the Prevention Program, 100% of subjects interviewed gave a general favorable consent in approaching rapid and not invasive screening, immediate return of the result, and a timely specialized approach and treatment of HIV positive subjects. Results from our study confirm that the rapid and alternative test may contribute to HIV prevention strategies and to the control of the spread of infection and HIV disease progression by reaching a larger population, particularly when and where regular screening procedures are difficult to obtain or are not preferred.

AB - The submerged portion of undiagnosed HIV infection in Italy is about 30% of subjects found seropositive. This fact represents one of the most important public health problems hindering the control of infection progression. This means we need to fight unawareness and social stigma and promote easy and friendly access to HIV test. We developed a Prevention Program called "EASY test Project", offering a new rapid HIV test on oral fluid, to evaluate the acceptability of an alternative, free and anonymous test available in different settings (on board a "Motor Home" at public events, Points of Care, STDs outpatient prevention units and GP surgeries). From December 2008 to December 2012 we performed 7,865 HIV saliva tests, with 50 new infections found (0.6% of the total) out of 140,000 informed subjects. From the self-reported characteristics of respondents, the population approaching the EAST test project was represented by males (70%) aged between 20 and 50 years, 61% with a medium-high education level, 62% homosexuals (MSM), 88% reported unsafe sexual behaviours, and 48% had never undergone an HIV screening test. In five years of the Prevention Program, 100% of subjects interviewed gave a general favorable consent in approaching rapid and not invasive screening, immediate return of the result, and a timely specialized approach and treatment of HIV positive subjects. Results from our study confirm that the rapid and alternative test may contribute to HIV prevention strategies and to the control of the spread of infection and HIV disease progression by reaching a larger population, particularly when and where regular screening procedures are difficult to obtain or are not preferred.

KW - HIV positive submerged people

KW - HIV prevention

KW - HIV screening test

KW - Late HIV diagnosis

KW - Saliva/oral fluid test

UR - http://www.scopus.com/inward/record.url?scp=84878869481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878869481&partnerID=8YFLogxK

M3 - Article

C2 - 23686118

AN - SCOPUS:84878869481

VL - 36

SP - 121

EP - 132

JO - New Microbiologica

JF - New Microbiologica

SN - 1121-7138

IS - 2

ER -