Cross-talk between hematopoiesis and angiogenesis signaling pathways

Domenico Ribatti, Angelo Vacca, Beatrice Nico, Roberto Ria, Franco Dammacco

Research output: Contribution to journalArticle

Abstract

The relationship between hematopoietic cells and endothelial cells has been seen as an indication that a common progenitor, the hemangioblast, gives rise to both cell types in the yolk sac, the initial site of hematopoiesis and blood vessel formation during mammalian development. The existence of angioblast-like circulating endothelial precursor cells in adults humans has recently been suggested. In this review, we have summarized the principle mechanisms involved in the cross-talk signaling pathway between hematopoiesis and angiogenesis in order to further understand how the hematopoietic and vascular systems are established during the development.

Original languageEnglish
Pages (from-to)537-543
Number of pages7
JournalCurrent Molecular Medicine
Volume2
Issue number6
DOIs
Publication statusPublished - Sep 2002

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Endothelial cells
Hematopoiesis
Blood vessels
Blood Vessels
Hemangioblasts
Endothelial Cells
Hematopoietic System
Yolk Sac

Keywords

  • Angiogenesis
  • Endothelial precursor cells
  • Hematopoiesis
  • Signaling pathway

ASJC Scopus subject areas

  • Biochemistry

Cite this

Cross-talk between hematopoiesis and angiogenesis signaling pathways. / Ribatti, Domenico; Vacca, Angelo; Nico, Beatrice; Ria, Roberto; Dammacco, Franco.

In: Current Molecular Medicine, Vol. 2, No. 6, 09.2002, p. 537-543.

Research output: Contribution to journalArticle

Ribatti, D, Vacca, A, Nico, B, Ria, R & Dammacco, F 2002, 'Cross-talk between hematopoiesis and angiogenesis signaling pathways', Current Molecular Medicine, vol. 2, no. 6, pp. 537-543. https://doi.org/10.2174/1566524023362195
Ribatti, Domenico ; Vacca, Angelo ; Nico, Beatrice ; Ria, Roberto ; Dammacco, Franco. / Cross-talk between hematopoiesis and angiogenesis signaling pathways. In: Current Molecular Medicine. 2002 ; Vol. 2, No. 6. pp. 537-543.
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