Abstract
The relationship between hematopoietic cells and endothelial cells has been seen as an indication that a common progenitor, the hemangioblast, gives rise to both cell types in the yolk sac, the initial site of hematopoiesis and blood vessel formation during mammalian development. The existence of angioblast-like circulating endothelial precursor cells in adults humans has recently been suggested. In this review, we have summarized the principle mechanisms involved in the cross-talk signaling pathway between hematopoiesis and angiogenesis in order to further understand how the hematopoietic and vascular systems are established during the development.
| Original language | English |
|---|---|
| Pages (from-to) | 537-543 |
| Number of pages | 7 |
| Journal | Current Molecular Medicine |
| Volume | 2 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Sep 2002 |
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Keywords
- Angiogenesis
- Endothelial precursor cells
- Hematopoiesis
- Signaling pathway
ASJC Scopus subject areas
- Biochemistry
Cite this
Cross-talk between hematopoiesis and angiogenesis signaling pathways. / Ribatti, Domenico; Vacca, Angelo; Nico, Beatrice; Ria, Roberto; Dammacco, Franco.
In: Current Molecular Medicine, Vol. 2, No. 6, 09.2002, p. 537-543.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cross-talk between hematopoiesis and angiogenesis signaling pathways
AU - Ribatti, Domenico
AU - Vacca, Angelo
AU - Nico, Beatrice
AU - Ria, Roberto
AU - Dammacco, Franco
PY - 2002/9
Y1 - 2002/9
N2 - The relationship between hematopoietic cells and endothelial cells has been seen as an indication that a common progenitor, the hemangioblast, gives rise to both cell types in the yolk sac, the initial site of hematopoiesis and blood vessel formation during mammalian development. The existence of angioblast-like circulating endothelial precursor cells in adults humans has recently been suggested. In this review, we have summarized the principle mechanisms involved in the cross-talk signaling pathway between hematopoiesis and angiogenesis in order to further understand how the hematopoietic and vascular systems are established during the development.
AB - The relationship between hematopoietic cells and endothelial cells has been seen as an indication that a common progenitor, the hemangioblast, gives rise to both cell types in the yolk sac, the initial site of hematopoiesis and blood vessel formation during mammalian development. The existence of angioblast-like circulating endothelial precursor cells in adults humans has recently been suggested. In this review, we have summarized the principle mechanisms involved in the cross-talk signaling pathway between hematopoiesis and angiogenesis in order to further understand how the hematopoietic and vascular systems are established during the development.
KW - Angiogenesis
KW - Endothelial precursor cells
KW - Hematopoiesis
KW - Signaling pathway
UR - http://www.scopus.com/inward/record.url?scp=0036727201&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036727201&partnerID=8YFLogxK
U2 - 10.2174/1566524023362195
DO - 10.2174/1566524023362195
M3 - Article
C2 - 12243246
AN - SCOPUS:0036727201
VL - 2
SP - 537
EP - 543
JO - Current Molecular Medicine
JF - Current Molecular Medicine
SN - 1566-5240
IS - 6
ER -