Abstract
Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.
| Original language | English |
|---|---|
| Pages (from-to) | 89-91 |
| Number of pages | 3 |
| Journal | OncoImmunology |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2012 |
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Keywords
- Cancer associated fibroblasts
- Dendritic cells
- Pancreatic cancer
- Th2-type inflammation
- Thymic stromal lymphopoietin
ASJC Scopus subject areas
- Immunology and Allergy
- Oncology
- Immunology
Cite this
Cross-talk within the tumor microenvironment mediates Th2-type inflammation in pancreatic cancer. / Protti, Maria Pia; De Monte, Lucia.
In: OncoImmunology, Vol. 1, No. 1, 2012, p. 89-91.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cross-talk within the tumor microenvironment mediates Th2-type inflammation in pancreatic cancer
AU - Protti, Maria Pia
AU - De Monte, Lucia
PY - 2012
Y1 - 2012
N2 - Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.
AB - Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.
KW - Cancer associated fibroblasts
KW - Dendritic cells
KW - Pancreatic cancer
KW - Th2-type inflammation
KW - Thymic stromal lymphopoietin
UR - http://www.scopus.com/inward/record.url?scp=84870366290&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870366290&partnerID=8YFLogxK
U2 - 10.4161/onci.1.1.17939
DO - 10.4161/onci.1.1.17939
M3 - Article
AN - SCOPUS:84870366290
VL - 1
SP - 89
EP - 91
JO - OncoImmunology
JF - OncoImmunology
SN - 2162-4011
IS - 1
ER -