Cross-talk within the tumor microenvironment mediates Th2-type inflammation in pancreatic cancer

Research output: Contribution to journalArticle

Abstract

Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalOncoImmunology
Volume1
Issue number1
DOIs
Publication statusPublished - 2012

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Tumor-Infiltrating Lymphocytes
Tumor Microenvironment
Pancreatic Neoplasms
Chemokines
Cytokines
Inflammation
Survival
Growth
Neoplasms

Keywords

  • Cancer associated fibroblasts
  • Dendritic cells
  • Pancreatic cancer
  • Th2-type inflammation
  • Thymic stromal lymphopoietin

ASJC Scopus subject areas

  • Immunology and Allergy
  • Oncology
  • Immunology

Cite this

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abstract = "Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.",
keywords = "Cancer associated fibroblasts, Dendritic cells, Pancreatic cancer, Th2-type inflammation, Thymic stromal lymphopoietin",
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KW - Thymic stromal lymphopoietin

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