CRosser As First choice for crossing Totally occluded coronary arteries (CRAFT Registry): Focus on conventional angiography and computed tomography angiography predictors of success

Héctor M. García-García, Salvatore Brugaletta, Carlos A G Van Mieghem, Nieves Gonzalo, Roberto Diletti, Josep Gomez-Lara, Flavio Airoldi, Mauro Carlino, Davide Tavano, Alaide Chieffo, Matteo Montorfano, Iassen Michev, Antonio Colombo, Martin Van Der Ent, Patrick W. Serruys

Research output: Contribution to journalArticle


Aims: We investigated the use of the CROSSER catheter, a CTO crossing device based upon high frequency mechanical vibration, as a first resort to treat patients with chronic total occlusions (CTO) while describing angiographic and computed tomography coronary angiography (CTCA) serving as predictors for success. Methods and results: Eighty consecutive patients were enrolled in this prospective multicentre registry of patients treated for a CTO. For 76.3% of the patients, this was the first attempt to open the CTO. Overall success rate was 75%. By conventional coronary angiography, the length of the occlusion was 26.7±14.1 mm and there was a difference in successful vs. unsuccessful cases (24.5±13.9 and 32.8±13.1, p=0.02). The presence of angulation, as defined qualitatively, was more prevalent in failed cases (60.0% vs. 32.2%, p=0.03). The mean ratio CROSSER distance within the occlusion site and length of the occlusion showed a trend towards statistical significance in successful procedures (0.56±0.90 vs. 0.30±0.34, p=0.08). During hospitali- sation, two patients had a non-fatal myocardial infarction. One patient experienced delayed onset of tamponade six hours postprocedure. At 30 days, two patients had PCI in a non-treated vessel and one patient had a transient ischaemic attack. Relation to the CROSSER catheter was inconclusive. Conclusions: The success rate of the use of a dedicated-CTO device -the CROSSER catheter- as a first choice to open a chronic total occlusion was 75%. By multivariate analysis, in a subset of patients that were imaged with computed tomography coronary angiography, the absence of angulation was related with higher success rate.

Original languageEnglish
Pages (from-to)480-486
Number of pages7
Issue number4
Publication statusPublished - Aug 2011



  • Chronic total occlusion
  • Computed tomography coronary angiography
  • Radiation exposure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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