Cryoprecipitate-poor plasma fraction (cryosupernatant) in the treatment of thrombotic thrombocytopenic purpura at onset. A report of four cases

Cesare Perotti, Lorella Torretta, Ermete Molinari, Laura Salvaneschi

Research output: Contribution to journalArticle

Abstract

Treatment of thrombotic thrombocytopenic purpura (TTP) with cryoprecipitate-poor plasma (cryosupernatant) as substitution liquid has brought a portion of the relapsing forms of this syndrome under control. We experimented the use of plasma exchange (PE) with CPP as plasma substitute in the initial treatment of four patients with TTP at onset, in an attempt to elicit a faster response to therapy. We observed a clinical response in the four patients treated; however, laboratory indices of complete and stable response (platelet count, serum lactate dehydrogenase level) did not normalize in concert with clinical improvement.

Original languageEnglish
Pages (from-to)175-177
Number of pages3
JournalHaematologica
Volume81
Issue number2
Publication statusPublished - Mar 1996

Keywords

  • Cryoprecipitate-poor plasma fraction
  • Plasmapheresis
  • Thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Hematology

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