Cryptogenic haemoptysis in smokers: Angiography and results of embolisation in 35 patients

L. Menchini, M. Remy-Jardin, J. B. Faivre, M. C. Copin, P. Ramon, R. Matran, V. Deken, A. Duhamel, J. Remy

Research output: Contribution to journalArticle

Abstract

The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright

Original languageEnglish
Pages (from-to)1031-1039
Number of pages9
JournalEuropean Respiratory Journal
Volume34
Issue number5
DOIs
Publication statusPublished - Nov 2009

Fingerprint

Hemoptysis
Angiography
Chronic Obstructive Pulmonary Disease
Hemorrhage
Bronchial Arteries
Recurrence
Chronic Bronchitis
Tobacco Use
Bronchoscopy
Blood Vessels
Comorbidity
Smoking
Inflammation

Keywords

  • Bronchial arteries
  • Chronic obstructive pulmonary disease
  • Smoker's lung

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Menchini, L., Remy-Jardin, M., Faivre, J. B., Copin, M. C., Ramon, P., Matran, R., ... Remy, J. (2009). Cryptogenic haemoptysis in smokers: Angiography and results of embolisation in 35 patients. European Respiratory Journal, 34(5), 1031-1039. https://doi.org/10.1183/09031936.00018709

Cryptogenic haemoptysis in smokers : Angiography and results of embolisation in 35 patients. / Menchini, L.; Remy-Jardin, M.; Faivre, J. B.; Copin, M. C.; Ramon, P.; Matran, R.; Deken, V.; Duhamel, A.; Remy, J.

In: European Respiratory Journal, Vol. 34, No. 5, 11.2009, p. 1031-1039.

Research output: Contribution to journalArticle

Menchini, L, Remy-Jardin, M, Faivre, JB, Copin, MC, Ramon, P, Matran, R, Deken, V, Duhamel, A & Remy, J 2009, 'Cryptogenic haemoptysis in smokers: Angiography and results of embolisation in 35 patients', European Respiratory Journal, vol. 34, no. 5, pp. 1031-1039. https://doi.org/10.1183/09031936.00018709
Menchini, L. ; Remy-Jardin, M. ; Faivre, J. B. ; Copin, M. C. ; Ramon, P. ; Matran, R. ; Deken, V. ; Duhamel, A. ; Remy, J. / Cryptogenic haemoptysis in smokers : Angiography and results of embolisation in 35 patients. In: European Respiratory Journal. 2009 ; Vol. 34, No. 5. pp. 1031-1039.
@article{76009c8739bc40e29765a82072fb7adb,
title = "Cryptogenic haemoptysis in smokers: Angiography and results of embolisation in 35 patients",
abstract = "The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91{\%}) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80{\%}) patients, and normal vascularisation in seven (20{\%}). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85{\%}), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94{\%}) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright",
keywords = "Bronchial arteries, Chronic obstructive pulmonary disease, Smoker's lung",
author = "L. Menchini and M. Remy-Jardin and Faivre, {J. B.} and Copin, {M. C.} and P. Ramon and R. Matran and V. Deken and A. Duhamel and J. Remy",
year = "2009",
month = "11",
doi = "10.1183/09031936.00018709",
language = "English",
volume = "34",
pages = "1031--1039",
journal = "European Journal of Respiratory Diseases",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "5",

}

TY - JOUR

T1 - Cryptogenic haemoptysis in smokers

T2 - Angiography and results of embolisation in 35 patients

AU - Menchini, L.

AU - Remy-Jardin, M.

AU - Faivre, J. B.

AU - Copin, M. C.

AU - Ramon, P.

AU - Matran, R.

AU - Deken, V.

AU - Duhamel, A.

AU - Remy, J.

PY - 2009/11

Y1 - 2009/11

N2 - The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright

AB - The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright

KW - Bronchial arteries

KW - Chronic obstructive pulmonary disease

KW - Smoker's lung

UR - http://www.scopus.com/inward/record.url?scp=71049178761&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=71049178761&partnerID=8YFLogxK

U2 - 10.1183/09031936.00018709

DO - 10.1183/09031936.00018709

M3 - Article

C2 - 19357153

AN - SCOPUS:71049178761

VL - 34

SP - 1031

EP - 1039

JO - European Journal of Respiratory Diseases

JF - European Journal of Respiratory Diseases

SN - 0903-1936

IS - 5

ER -