Abstract
The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright
| Original language | English |
|---|---|
| Pages (from-to) | 1031-1039 |
| Number of pages | 9 |
| Journal | European Respiratory Journal |
| Volume | 34 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Nov 2009 |
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Keywords
- Bronchial arteries
- Chronic obstructive pulmonary disease
- Smoker's lung
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Cryptogenic haemoptysis in smokers : Angiography and results of embolisation in 35 patients. / Menchini, L.; Remy-Jardin, M.; Faivre, J. B.; Copin, M. C.; Ramon, P.; Matran, R.; Deken, V.; Duhamel, A.; Remy, J.
In: European Respiratory Journal, Vol. 34, No. 5, 11.2009, p. 1031-1039.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cryptogenic haemoptysis in smokers
T2 - Angiography and results of embolisation in 35 patients
AU - Menchini, L.
AU - Remy-Jardin, M.
AU - Faivre, J. B.
AU - Copin, M. C.
AU - Ramon, P.
AU - Matran, R.
AU - Deken, V.
AU - Duhamel, A.
AU - Remy, J.
PY - 2009/11
Y1 - 2009/11
N2 - The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright
AB - The aim of the present study was to describe angiographic findings and embolisation results in smokers with haemoptysis. We retrospectively reviewed the clinical data and angiographic findings from 35 patients with smoking-related bronchopulmonary disease and no associated comorbidity, who were referred for embolisation for mild (n=6), moderate (n=14) and severe (n=15) haemoptysis. Spirometric classification subdivided our population into: 16 patients with chronic bronchitis but no airflow limitation; and 19 patients with chronic obstructive pulmonary disease (COPD) (stage I: n=12; stage II: n=5; stage III: n=2). Bronchoscopy depicted focal submucosal vascular abnormalities in three patients and only endobronchial inflammation in 32 (91%) patients. Bronchial artery angiography revealed moderate (n=18) or severe (n=10) hypervascularisation in 28 (80%) patients, and normal vascularisation in seven (20%). No statistically significant difference was observed between the angiographic findings and the severity of COPD, tobacco consumption or the amount of bleeding. Cessation of bleeding was obtained by embolisation in 29 out of the 34 technically successful procedures (85%), requiring surgery in three out of five patients with recurrence. Follow-up (mean duration 7 yrs) demonstrated no recurrence of bleeding in 32 (94%) out of 34 patients and excluded late endobronchial malignancy. Smokers with various stages of COPD severity may suffer from haemoptysis that is efficiently treatable by endovascular treatment. Copyright
KW - Bronchial arteries
KW - Chronic obstructive pulmonary disease
KW - Smoker's lung
UR - http://www.scopus.com/inward/record.url?scp=71049178761&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71049178761&partnerID=8YFLogxK
U2 - 10.1183/09031936.00018709
DO - 10.1183/09031936.00018709
M3 - Article
C2 - 19357153
AN - SCOPUS:71049178761
VL - 34
SP - 1031
EP - 1039
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 5
ER -