CT-Guided fine-needle aspiration cytology of solitary pulmonary nodules: A prospective, randomized study of immediate cytologic evaluation

Luigi Santambrogio, Mario Nosotti, Nadia Bellaviti, Gianni Pavoni, Ferdinando Radice, Valentina Caputo

Research output: Contribution to journalArticlepeer-review

Abstract

Study objective: To evaluate the immediate cytologic assessment during CT-guided fine-needle aspiration cytology (FNAC) in the diagnosis of operable indeterminate solitary pulmonary nodules (SPNs). Design: Prospective randomized study. Patients and methods: Two hundred twenty patients with SPN undergoing CT-guided FNAC were divided into two groups. In the first one (group A, 110 patients), a cytologist assessed the adequacy of the sample obtained immediately, and when the sample was considered inadequate, fine- needle aspiration (FNA) was repeated. In the second group (B, 110 patients), an immediate cytologic examination was not performed, but only a gross assessment by the surgeon. Histologic study of the SPN was possible in 217 cases, whereas three patients were followed up radiologically. Results: Adequate samples were obtained in 100% of group A and 88% of group B (p

Original languageEnglish
Pages (from-to)423-425
Number of pages3
JournalChest
Volume112
Issue number2
Publication statusPublished - 1997

Keywords

  • Biopsies, technology
  • Lung, biopsy
  • Lung, neoplasm
  • Lung, nodule

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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