CT-guided pancreatic percutaneous fine-needle biopsy in differential diagnosis between pancreatic cancer and chronic pancreatitis

M. Carlucci, A. Zerbi, D. Parolini, S. Sironi, A. Vanzulli, C. Staudacher, A. Faravelli, P. Garancini, A. Del Maschio, V. Di Carlo

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Abstract

Differential diagnosis between pancreatic cancer and chronic pancreatitis is still difficult to establish. In 63 patients with suspected pancreatic neoplasm we performed: serum CA 19-9 assessment, abdominal ultrasound, CT scan and CT-guided pancreatic percutaneous fine-needle biopsy. The conclusive diagnosis was pancreatic cancer in 40 patients and chronic pancreatitis in 23 patients. With regard to the differential diagnosis, sensitivity and specificity were respectively 80% and 78% for serum CA 19-9, 75% and 65% for abdominal US, 85% and 70% for CT scan, 00% and 87% for percutaneous fine-needle biopsy. We conclude that CT-guided percutaneous fine-needle biopsy is the most reliable method for differential diagnosis between pancreatic cancer and chronic pancreatitis.

Original languageEnglish
Pages (from-to)309-317
Number of pages9
JournalHPB Surgery
Volume1
Issue number4
Publication statusPublished - 1989

Keywords

  • chronic pancreatitis
  • CT scan
  • fine-needle biopsy
  • pancreatic cancer

ASJC Scopus subject areas

  • Hepatology
  • Surgery

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    Carlucci, M., Zerbi, A., Parolini, D., Sironi, S., Vanzulli, A., Staudacher, C., Faravelli, A., Garancini, P., Del Maschio, A., & Di Carlo, V. (1989). CT-guided pancreatic percutaneous fine-needle biopsy in differential diagnosis between pancreatic cancer and chronic pancreatitis. HPB Surgery, 1(4), 309-317.