TC-guidata delle masse renali in pazienti selezionati

Translated title of the contribution: CT-guided percutaneous cryoablation of renal masses in selected Patients Crioablazione percutanea

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

PurposE. We analysed our experience with computed tomography (CT)-guided percutaneous cryoablation (PCA) in patients who were not surgical candidates or refused surgery for small to medium-sized renal masses. Materials and methods. Two freezing cycles were applied and separated by a passive warming cycle using 1.7- and 2.4-mm cryoprobes under either general anaesthesia or sedation based on patient positioning and respiratory status. Postoperative monitoring included haematological and biochemistry evaluation and CT scan 24 h after PCA. Follow-up consisted of a multislice CT scan at 1 month and every 3 months in the first year then every 6 months thereafter. Results. Thirty-seven patients (38 lesions) underwent 40 PCA procedures; 5/37 (13.5%) had a solitary kidneY. Median mass size was 35 (range 12-70) mm. No complications occurred during the procedurE. Clavien grade ?2 anaemia occurred in two patients (5.4 %): one patient required 1 U of packed red blood cells; the other required an arterial embolisation. Serum creatinine did not increase in any casE. Two patients showed persisting or recurrent disease at 1 and 9 months, respectively, and both could be re-treated with PCA. All other patients showed a hypodense mass 3 months after PCA, with no contrast enhancement. Subsequent examinations showed that lesion sizes decreased and CT densitometry remained stable or increased minimally, also with no contrast enhancement. Conclusions. PCA proved relatively easy and safe and could be considered an effective alternative for patients who are not surgical candidates or refuse surgery, as well as in patients with medium-sized lesions.

Original languageItalian
Pages (from-to)593-605
Number of pages13
JournalRadiologia Medica
Volume117
Issue number4
DOIs
Publication statusPublished - Jun 2012

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Cryosurgery
Tomography
Kidney
Patient Positioning
Multidetector Computed Tomography
Densitometry
Biochemistry
General Anesthesia
Freezing
Anemia
Creatinine
Erythrocytes
Serum

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

@article{b518e2e8c9214f53b73d1fd0a50e8bfe,
title = "TC-guidata delle masse renali in pazienti selezionati",
abstract = "PurposE. We analysed our experience with computed tomography (CT)-guided percutaneous cryoablation (PCA) in patients who were not surgical candidates or refused surgery for small to medium-sized renal masses. Materials and methods. Two freezing cycles were applied and separated by a passive warming cycle using 1.7- and 2.4-mm cryoprobes under either general anaesthesia or sedation based on patient positioning and respiratory status. Postoperative monitoring included haematological and biochemistry evaluation and CT scan 24 h after PCA. Follow-up consisted of a multislice CT scan at 1 month and every 3 months in the first year then every 6 months thereafter. Results. Thirty-seven patients (38 lesions) underwent 40 PCA procedures; 5/37 (13.5{\%}) had a solitary kidneY. Median mass size was 35 (range 12-70) mm. No complications occurred during the procedurE. Clavien grade ?2 anaemia occurred in two patients (5.4 {\%}): one patient required 1 U of packed red blood cells; the other required an arterial embolisation. Serum creatinine did not increase in any casE. Two patients showed persisting or recurrent disease at 1 and 9 months, respectively, and both could be re-treated with PCA. All other patients showed a hypodense mass 3 months after PCA, with no contrast enhancement. Subsequent examinations showed that lesion sizes decreased and CT densitometry remained stable or increased minimally, also with no contrast enhancement. Conclusions. PCA proved relatively easy and safe and could be considered an effective alternative for patients who are not surgical candidates or refuse surgery, as well as in patients with medium-sized lesions.",
keywords = "Percutaneous cryoablation, Renal cell cancer",
author = "C. Spreafico and N. Nicolai and R. Lanocita and C. Morosi and M. Catanzaro and E. Civelli and T. Torelli and S. Stagni and L. Piva and Frigerio, {L. F.} and A. Marchian{\`o} and R. Salvioni",
year = "2012",
month = "6",
doi = "10.1007/s11547-011-0742-1",
language = "Italian",
volume = "117",
pages = "593--605",
journal = "Radiologia Medica",
issn = "0033-8362",
publisher = "Springer-Verlag Italia s.r.l.",
number = "4",

}

TY - JOUR

T1 - TC-guidata delle masse renali in pazienti selezionati

AU - Spreafico, C.

AU - Nicolai, N.

AU - Lanocita, R.

AU - Morosi, C.

AU - Catanzaro, M.

AU - Civelli, E.

AU - Torelli, T.

AU - Stagni, S.

AU - Piva, L.

AU - Frigerio, L. F.

AU - Marchianò, A.

AU - Salvioni, R.

PY - 2012/6

Y1 - 2012/6

N2 - PurposE. We analysed our experience with computed tomography (CT)-guided percutaneous cryoablation (PCA) in patients who were not surgical candidates or refused surgery for small to medium-sized renal masses. Materials and methods. Two freezing cycles were applied and separated by a passive warming cycle using 1.7- and 2.4-mm cryoprobes under either general anaesthesia or sedation based on patient positioning and respiratory status. Postoperative monitoring included haematological and biochemistry evaluation and CT scan 24 h after PCA. Follow-up consisted of a multislice CT scan at 1 month and every 3 months in the first year then every 6 months thereafter. Results. Thirty-seven patients (38 lesions) underwent 40 PCA procedures; 5/37 (13.5%) had a solitary kidneY. Median mass size was 35 (range 12-70) mm. No complications occurred during the procedurE. Clavien grade ?2 anaemia occurred in two patients (5.4 %): one patient required 1 U of packed red blood cells; the other required an arterial embolisation. Serum creatinine did not increase in any casE. Two patients showed persisting or recurrent disease at 1 and 9 months, respectively, and both could be re-treated with PCA. All other patients showed a hypodense mass 3 months after PCA, with no contrast enhancement. Subsequent examinations showed that lesion sizes decreased and CT densitometry remained stable or increased minimally, also with no contrast enhancement. Conclusions. PCA proved relatively easy and safe and could be considered an effective alternative for patients who are not surgical candidates or refuse surgery, as well as in patients with medium-sized lesions.

AB - PurposE. We analysed our experience with computed tomography (CT)-guided percutaneous cryoablation (PCA) in patients who were not surgical candidates or refused surgery for small to medium-sized renal masses. Materials and methods. Two freezing cycles were applied and separated by a passive warming cycle using 1.7- and 2.4-mm cryoprobes under either general anaesthesia or sedation based on patient positioning and respiratory status. Postoperative monitoring included haematological and biochemistry evaluation and CT scan 24 h after PCA. Follow-up consisted of a multislice CT scan at 1 month and every 3 months in the first year then every 6 months thereafter. Results. Thirty-seven patients (38 lesions) underwent 40 PCA procedures; 5/37 (13.5%) had a solitary kidneY. Median mass size was 35 (range 12-70) mm. No complications occurred during the procedurE. Clavien grade ?2 anaemia occurred in two patients (5.4 %): one patient required 1 U of packed red blood cells; the other required an arterial embolisation. Serum creatinine did not increase in any casE. Two patients showed persisting or recurrent disease at 1 and 9 months, respectively, and both could be re-treated with PCA. All other patients showed a hypodense mass 3 months after PCA, with no contrast enhancement. Subsequent examinations showed that lesion sizes decreased and CT densitometry remained stable or increased minimally, also with no contrast enhancement. Conclusions. PCA proved relatively easy and safe and could be considered an effective alternative for patients who are not surgical candidates or refuse surgery, as well as in patients with medium-sized lesions.

KW - Percutaneous cryoablation

KW - Renal cell cancer

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U2 - 10.1007/s11547-011-0742-1

DO - 10.1007/s11547-011-0742-1

M3 - Articolo

VL - 117

SP - 593

EP - 605

JO - Radiologia Medica

JF - Radiologia Medica

SN - 0033-8362

IS - 4

ER -