Trattamento chirurgico radicale per carcinoma del colon-retto nel paziente anziano. Fattori prognostici e sopravvivenza a cinque anni

Translated title of the contribution: Curative resection for colorectal cancer in the elderly. Prognostic factors and five-year follow-up

C. Staudacher, A. Chiappa, A. P. Zbar, E. Bertani, F. Biella

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this perspective study was to evaluate which prognostic factors predict long-term survival and disease-free survival (DFS) of elderly patients (≥ 65 years) who underwent surgery for colorectal carcinoma. Between fanuary 1992 and December 1998, 196 colorectal cancer patients ≥ 65 years (114M; 82F; mean age: 75 years; range: 65-92) underwent surgery. One hundred forty-five (74%) of them underwent curative surgery and emergency surgery was more common in patients ≥ 75 years of age than among those younger than 75 years (39% vs 23%; p = 0.01). The overall peroperative mortality rate was 3% (n = 6). The median length of hospital stay was 18 days (range: 3-86 days). By univariate analysis, intraoperative bleeding (≥ 500 cc; p = 0.002), length of surgery (≥ 240 min.; p = 0.004), and rectal cancer (p = 0.0001) were associated with complications. By multivariate analysis, only rectal cancer (p = 0.002) was associated with complications. The overall 1, 3-, and 5-year survival rate and DFS rate were 97%, 82%, 74%, and. 86%, 64% and 60% respectively. Using multivariate analysis only tumour stage (p <0.0001) and peroperative blood transfusions (≥ 500 cc; p = 0.006) were associated with outcome. Treatment decisions in elderly patients with colorectal carcinoma should not be influenced by the chronologic age of the patient.

Translated title of the contributionCurative resection for colorectal cancer in the elderly. Prognostic factors and five-year follow-up
Original languageItalian
Pages (from-to)491-496
Number of pages6
JournalAnnali Italiani di Chirurgia
Volume71
Issue number4
Publication statusPublished - Jul 2000

ASJC Scopus subject areas

  • Surgery

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