Current chemotherapeutic strategies for rhabdomyosarcoma

Research output: Contribution to journalArticlepeer-review

Abstract

Rhabdomyosarcoma is a typical tumor of childhood and adolescence. Over the years there has been a gradual but important improvement in survival for patients with this tumor, despite its high grade of malignancy. These results are due to multidisciplinary treatment approaches including surgery, radiotherapy and especially chemotherapy. Rhabdomyosarcoma is a highly chemosensitive neoplasm, and the role of this therapeutic approach has also been clearly demonstrated in the adjuvant setting. This review covers current concepts on chemotherapy for rhabdomyosarcoma, with an overview of the results of the main clinical trials conducted over recent years and considerations of possible strategies for the near future. Recommendations for adult patients with rhabdomyosarcoma are also discussed, suggesting that these patients should be treated according to pediatric guidelines.

Original languageEnglish
Pages (from-to)283-294
Number of pages12
JournalExpert Review of Anticancer Therapy
Volume5
Issue number2
DOIs
Publication statusPublished - Apr 2005

Keywords

  • Chemotherapy
  • New drugs
  • Pediatric soft tissue sarcoma
  • Rhabdomyosarcoma
  • Risk stratification
  • Treatment protocols

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

Fingerprint Dive into the research topics of 'Current chemotherapeutic strategies for rhabdomyosarcoma'. Together they form a unique fingerprint.

Cite this