Current concepts for the diagnosis and management of eosinophilic granuloma of bone

Andrea Angelini, Andreas F. Mavrogenis, Eugenio Rimondi, Giuseppe Rossi, Pietro Ruggieri

Research output: Contribution to journalArticle


This review summarizes current concepts in the diagnosis and management of the patients with eosinophilic granuloma. Given the benign biology, the clinical course, and the pediatric group of patients that this condition more commonly affects, a treatment approach that carries a lower risk of complications while ensuring a successful cure is desirable. Variable treatment options have been reported with satisfactory results and a recurrence rate of less than 20 %. In this setting, symptomatic lesions that are accessible in the spine or the extremities may be treated with intralesional methylprednisolone injection after tissue biopsy for histological diagnosis.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalJournal of Orthopaedics and Traumatology
Publication statusAccepted/In press - Oct 21 2016



  • Bone tumors
  • Eosinophilic granuloma
  • Extremities
  • Methylprednisolone injection
  • Spine

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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