Current concepts in the biopsy of musculoskeletal tumors

Costantino Errani, Francesco Traina, Fabrizio Perna, Carlotta Calamelli, Cesare Faldini

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

In the management of bone and soft tissue tumors, accurate diagnosis, using a combination of clinical, radiographic, and histological data, is critical to optimize outcome. On occasion, diagnosis can be made by careful history, physical examination, and images alone. However, the ultimate diagnosis usually depends on histologic analysis by an experienced pathologist. Biopsy is a very important and complex surgery in the staging process. It must be done carefully, so as not to adversely affect the outcome. Technical considerations include proper location and orientation of the biopsy incision and meticulous hemostasis. It is necessary to obtain tissue for a histological diagnosis without spreading the tumor and so compromise the treatment. Furthermore, the surgeon does not open compartmental barriers, anatomic planes, joint space, and tissue area around neurovascular bundles. Nevertheless, avoid producing a hematoma. Biopsy should be carefully planned according to the site and definitive surgery and should be performed by an orthopedic surgeon with an experience in musculoskeletal oncology who will perform the definitive surgery. Improperly done, it can complicate patient care and sometimes even eliminate treatment options. Different biopsy techniques are suitable: fine-needle aspiration, core-needle biopsy, and incisional biopsy. The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist.

Original languageEnglish
Article number538152
JournalTheScientificWorldJournal
Volume2013
DOIs
Publication statusPublished - 2013

Fingerprint

Biopsy
tumor
Tumors
Neoplasms
Surgery
lesion
Tissue
bone
Needles
Large-Core Needle Biopsy
Fine Needle Biopsy
history
Oncology
Hemostasis
Hematoma
Orthopedics
Physical Examination
tissue
Patient Care
Joints

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Medicine(all)

Cite this

Current concepts in the biopsy of musculoskeletal tumors. / Errani, Costantino; Traina, Francesco; Perna, Fabrizio; Calamelli, Carlotta; Faldini, Cesare.

In: TheScientificWorldJournal, Vol. 2013, 538152, 2013.

Research output: Contribution to journalArticle

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