Current evidence of antifungal prophylaxis and therapy in pediatric patients

Mareva Giacchino, Giuseppe Maria Milano, Francesca Carraro, Stefania Bezzio, Anna Pegoraro, Franco Aversa, Simone Cesaro

Research output: Contribution to journalArticlepeer-review

Abstract

Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial infection but mortality rate remains high. This review is designed to help paediatric oncologists in choosing the appropriate anti-fungal strategy and agents for prophylaxis, empirical, pre-emptive and specific therapy on the basis of published evidence.

Original languageEnglish
Article numbere6
JournalPediatric Reports
Volume3
Issue number1
DOIs
Publication statusPublished - 2011

Keywords

  • Fungal infection
  • Pediatric malignancy

ASJC Scopus subject areas

  • Pediatrics

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