Current medical treatments for juvenile idiopathic arthritis

Research output: Contribution to journalArticle

Abstract

Juvenile idiopathic arthritis (JIA) differs markedly from adult rheumatoid arthritis. It is not a single disease, but an exclusion diagnosis that gather together all forms of arthritis that begin before the age of 16years, persist for more than 6weeks, and are of unknown origin. The advent of the new biological treatments has dramatically changed both the observed responses to treatment and the expectations of therapies. The implementation of an adequate legislation as well as the presence of international research networks of pediatric rheumatology have contributed to foster the conduct of controlled clinical trials and the development of validated outcome measures. This review will currently describe the methodological approach for performing clinical trials in JIA as well as the current available drug treatment.

Original languageEnglish
Article numberArticle 60
JournalFrontiers in Pharmacology
VolumeOCT
DOIs
Publication statusPublished - 2011

Keywords

  • Biological agents
  • Joint damage
  • Juvenile idiopathic arthritis
  • Small molecules

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology

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