Current role of radiotherapy in the treatment of locally advanced laryngeal carcinomas

Giorgio Cortesina, Antonella De Stefani, Andrea Cavalot, Roberto Albera, Paola Rosso, Mario Bussi

Research output: Contribution to journalArticle

Abstract

Background and Objectives: During the past few years, radiotherapy (RT) has been increasingly used in combination with surgery in the treatment of locally advanced laryngeal carcinomas to improve survival rates in patients with more extensive tumors. Methods: This is a retrospective study of a large series of stage HI and IV laryngeal carcinomas, and postoperative RT was indicated for some of these cases. We retrospectively reviewed the medical records of 380 patients with stage III and IV tumors, of which 163 (43%) underwent surgery only and 217 (57%) received surgery and postoperative RT. Results: The survival rates of patients who underwent surgery and RT were comparable to those of patients who underwent surgery only, but the former group was composed of subjects suffering from negative prognostic factors. Conclusions: The indications for combined treatment should be correlated with the prognostic factors to increase the survival rate of patients with stage III and IV laryngeal carcinoma. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)79-82
Number of pages4
JournalJournal of Surgical Oncology
Volume74
Issue number1
DOIs
Publication statusPublished - 2000

Keywords

  • Head and neck neoplasms
  • Laryngeal neoplasms
  • Radiotherapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

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