Current trends in patients with chronic total occlusions undergoing coronary CT angiography

Maksymilian P. Opolski, Bríain O. Hartaigh, Daniel S. Berman, Matthew J. Budoff, Stephan Achenbach, Mouaz Al-Mallah, Daniele Andreini, Filippo Cademartiri, Hyuk Jae Chang, Kavitha Chinnaiyan, Benjamin J W Chow, Martin Hadamitzky, Joerg Hausleiter, Gudrun Feuchtner, Yong Jin Kim, Philipp A. Kaufmann, Jonathon Leipsic, Erica Maffei, Gianluca Pontone, Gilbert RaffLeslee J. Shaw, Todd C. Villines, James K. Min

Research output: Contribution to journalArticlepeer-review


Objective: Data describing the prevalence, characteristics and management of coronary chronic total occlusions (CTOs) in patients undergoing coronary CT angiography (CCTA) have not been reported. The purpose of this study was to determine the prevalence, characteristics and treatment strategies of CTO identified by CCTA. Methods: We identified 23 745 patients who underwent CCTA for suspected coronary artery disease (CAD) from the prospective international CCTA registry. Baseline clinical data were collected, and allocation to early coronary revascularisation performed within 90 days of CCTA was determined. Multivariable hierarchical mixed-effects logistic regression reporting OR with 95% CI was performed. Results: The prevalence of CTO was 1.4% (342/23 745) in all patients and 6.2% in patients with obstructive CAD (≥50% stenosis). The presence of CTO was independently associated with male sex (OR 3.12, 95% CI 2.39 to 4.08, p

Original languageEnglish
Pages (from-to)1212-1218
Number of pages7
Issue number15
Publication statusPublished - Aug 1 2015

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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