Cutaneous infantile haemangiomas with intracranial and intraspinal involvement: A European multicentre experience and review

Andrea Diociaiuti, Claudia Carnevale, Eulalia Baselga Torres, Christine Léauté-Labrèze, Iria Neri, Roberta Rotunno, Lorenzo Figà-Talamanca, May El Hachem

Research output: Contribution to journalArticlepeer-review

Abstract

Infantile haemangiomas are very common benign tumours in the first months of life. They are mostly cutaneous; however, extracutaneous lesions are pos-sible, and occur in very rare cases in the central nervous system. A European multicentre observational retrospective study was conducted in the last 5 years. Seven patients with intracranial or intraspinal infantile haemangiomas were selected and treated with oral propranolol. Propranolol was interrupted after complete or almost complete resolution of infantile haemangiomas. All patients tolerated the treatment well without side-effects. Central nervous system infantile haemangiomas are probably underestimated due to the frequent absence of symptoms and their spontaneous involution. However, they should be in-vestigated in case of segmental cutaneous infantile haemangiomas, particularly on the head, neck, upper trunk, lumbar or sacral area in order to diagnose intra-central nervous system involvement at an early stage.

Original languageEnglish
Article numberadv00255
Pages (from-to)1-4
Number of pages4
JournalActa Dermato-Venereologica
Volume100
Issue number16
DOIs
Publication statusPublished - 2020

Keywords

  • Central nervous system
  • Infantile haemangioma
  • Oral propranolol

ASJC Scopus subject areas

  • Dermatology

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