TY - JOUR
T1 - Cutaneous localization of classic hodgkin lymphoma associated with mycosis fungoides: Report of a rare event and review of the literature
AU - Zanelli, Magda
AU - Ricci, Stefano
AU - Sanguedolce, Francesca
AU - Palicelli, Andrea
AU - Farnetti, Enrico
AU - Tafuni, Alessandro
AU - Zizzo, Maurizio
AU - Valli, Riccardo
AU - De Celis, Maria Isabel Alvarez
AU - Cavazza, Alberto
AU - Longo, Caterina
AU - Ascani, Stefano
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/10/11
Y1 - 2021/10/11
N2 - Mycosis fungoides and nodal classic Hodgkin lymphoma (cHL) have been reported to occur concurrently or sequentially in the same patient. A long-lasting mycosis fungoides more often precedes the onset of nodal cHL, although few cases of nodal cHL followed by mycosis fungoides have been observed. Skin involvement is a rare manifestation of cHL that may be observed in the setting of advanced disease. The decrease in skin involvement in cHL is mainly due to the improved therapeutic strategies. The concurrent presence of mycosis fungoides and cutaneous localization of classic Hodgkin lymphoma represents a very uncommon event, with only two cases reported so far. Herein, we describe the case of a 71-year-old man, with a history of recurrent nodal cHL, who developed MF and, subsequently, the cutaneous localization of cHL. The clinicopathological features of the two diseases are described focusing on the main differential diagnoses to be taken into consideration, and a review of the literature is performed.
AB - Mycosis fungoides and nodal classic Hodgkin lymphoma (cHL) have been reported to occur concurrently or sequentially in the same patient. A long-lasting mycosis fungoides more often precedes the onset of nodal cHL, although few cases of nodal cHL followed by mycosis fungoides have been observed. Skin involvement is a rare manifestation of cHL that may be observed in the setting of advanced disease. The decrease in skin involvement in cHL is mainly due to the improved therapeutic strategies. The concurrent presence of mycosis fungoides and cutaneous localization of classic Hodgkin lymphoma represents a very uncommon event, with only two cases reported so far. Herein, we describe the case of a 71-year-old man, with a history of recurrent nodal cHL, who developed MF and, subsequently, the cutaneous localization of cHL. The clinicopathological features of the two diseases are described focusing on the main differential diagnoses to be taken into consideration, and a review of the literature is performed.
KW - Classic Hodgkin lymphoma
KW - Mycosis fungoides
KW - Skin
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U2 - 10.3390/life11101069
DO - 10.3390/life11101069
M3 - Article
AN - SCOPUS:85117528055
VL - 11
JO - Life
JF - Life
SN - 0024-3019
IS - 10
M1 - 1069
ER -