Cutaneous metastasis from vulvar squamous cell carcinoma: A rare occurrence that should not be forgotten

Nicolò Bizzarri, Valerio Gaetano Vellone, Luca Parodi, Luana Calanni Fraccono, Valentina Ghirardi, Sergio Costantini, Mario Valenzano Menada, Paolo Sala

Research output: Contribution to journalArticle

Abstract

Vulvar cancer accounts for 5% of the female genital tract cancers. Cutaneous metastases from vulvar cancer are extremely rare and for this reason, it can be difficult to reach a diagnosis with a consequent delay in the treatment. A systematic literature review of articles on this subject was conducted through a MEDLINE-based search for articles published in English or French. To date, 16 cases (including ours unpublished) of cutaneous metastasis from vulvar cancer have been reported. Cutaneous metastasis can occur from any stage of vulvar cancer, even after a short period. Different treatments have been described but none of them seems to be more effective. In all reported cases the prognosis was very poor. Every time a vulvar cancer survivor shows a suspicious cutaneous lesion, this should be biopsied to exclude skin relapse.

Original languageEnglish
Pages (from-to)975-981
Number of pages7
JournalJournal of Obstetrics and Gynaecology
Volume37
Issue number8
DOIs
Publication statusPublished - Jan 1 2017

Keywords

  • Cutaneous metastasis
  • Recurrence
  • Skin metastasis
  • Vulvar squamous cell carcinoma

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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  • Cite this

    Bizzarri, N., Vellone, V. G., Parodi, L., Fraccono, L. C., Ghirardi, V., Costantini, S., Menada, M. V., & Sala, P. (2017). Cutaneous metastasis from vulvar squamous cell carcinoma: A rare occurrence that should not be forgotten. Journal of Obstetrics and Gynaecology, 37(8), 975-981. https://doi.org/10.1080/01443615.2017.1318269