Abstract
The postocclusive hyperaemic reaction before and after a single 1 h application of a potent corticoid (clobetasol 0.05% in ointment) was recorded by means of laser Doppler velocimetry in order to elucidate different racial responses in skin vasoconstriction. Fourteen young male subjects entered the study (eight Caucasians, six Blacks). Reactive hyperaemia was recorded after 4 min of occlusion of the forearm blood flow. The following parameters of the hyperaemic reaction were investigated: area under the curve response, peak response, rise of blood flow slope to peak and decay of blood flow slope after peak. Different responses were recorded in the Black subjects after the vasoconstrictive stimulus compared to the Caucasians, namely: decreased area under the curve response (P
| Original language | English |
|---|---|
| Pages (from-to) | 787-794 |
| Number of pages | 8 |
| Journal | British Journal of Dermatology |
| Volume | 120 |
| Issue number | 6 |
| Publication status | Published - 1989 |
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ASJC Scopus subject areas
- Dermatology
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Cutaneous reactive hyperaemia : racial differences induced by corticoid application. / Berardesca, E.; Maibach, H.
In: British Journal of Dermatology, Vol. 120, No. 6, 1989, p. 787-794.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cutaneous reactive hyperaemia
T2 - racial differences induced by corticoid application
AU - Berardesca, E.
AU - Maibach, H.
PY - 1989
Y1 - 1989
N2 - The postocclusive hyperaemic reaction before and after a single 1 h application of a potent corticoid (clobetasol 0.05% in ointment) was recorded by means of laser Doppler velocimetry in order to elucidate different racial responses in skin vasoconstriction. Fourteen young male subjects entered the study (eight Caucasians, six Blacks). Reactive hyperaemia was recorded after 4 min of occlusion of the forearm blood flow. The following parameters of the hyperaemic reaction were investigated: area under the curve response, peak response, rise of blood flow slope to peak and decay of blood flow slope after peak. Different responses were recorded in the Black subjects after the vasoconstrictive stimulus compared to the Caucasians, namely: decreased area under the curve response (P
AB - The postocclusive hyperaemic reaction before and after a single 1 h application of a potent corticoid (clobetasol 0.05% in ointment) was recorded by means of laser Doppler velocimetry in order to elucidate different racial responses in skin vasoconstriction. Fourteen young male subjects entered the study (eight Caucasians, six Blacks). Reactive hyperaemia was recorded after 4 min of occlusion of the forearm blood flow. The following parameters of the hyperaemic reaction were investigated: area under the curve response, peak response, rise of blood flow slope to peak and decay of blood flow slope after peak. Different responses were recorded in the Black subjects after the vasoconstrictive stimulus compared to the Caucasians, namely: decreased area under the curve response (P
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M3 - Article
C2 - 2757940
AN - SCOPUS:0024374882
VL - 120
SP - 787
EP - 794
JO - British Journal of Dermatology
JF - British Journal of Dermatology
SN - 0007-0963
IS - 6
ER -