Cutaneous vasculitis and reactive arthritis folowing respiratory infection due to Chlamyda pneumoniae: Report of a case

Alesssandro Cascina, Alessia Bianco Marone, Patrizia Mangiarotti, Carlo Maurizio Montecucco, Federica Meloni

Research output: Contribution to journalArticlepeer-review

Abstract

Unlike Chlamydia trachomatis and C. psittaci, the association of C. pneumoniae infection with immunological complications, such as reactive arthritis (ReA) or erythema nodosum (EN) has been rarely reported. Here we present the case history of a patient with C. pneumoniae community acquired pneumonia (CAP) who subsequently developed a ReA and a cutaneous vasculitis. A 45-year-old HLA B27 negative male developed an asymmetric and additive arthritis and a cutaneous leukocytoclastic vasculitis with IgM and complement papillary deposition along hypodermic vessel walls about three weeks after the onset of respiratory symptoms. The diagnosis of chronic Chlamydia pneumoniae infection was based on serology and PCR. Cultural and serological investigations for other infectious agents commonly involved in ReA were negative. This is the first report on the occurrence of two immune-based complications, associated to Chlamydia pneumoniae infection. Therefore, since this infection is very common in our population, although often asymptomatic, should be systematically considered as a common causative agent of ReA and of vasculitis.

Original languageEnglish
Pages (from-to)845-847
Number of pages3
JournalClinical and Experimental Rheumatology
Volume20
Issue number6
Publication statusPublished - Dec 2002

Keywords

  • Chlamydia pneumoniae
  • Reactive arthritis
  • Vasculitis

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

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