Cutoff score of the sexual interest and desire inventory-female for diagnosis of hypoactive sexual desire disorder

Anita H. Clayton, Robert T. Segraves, David Bakish, David Goldmeier, Jean Tignol, Rik H W Van Lunsen, Rossella E. Nappi, Glen Wunderlich, Toshio Kimura, Diane J. Lewis-D'Agostino, Robert Pyke

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To determine the most appropriate cutoff value for the Sexual Interest and Desire Inventory-Female (SIDI-F) score to discriminate between women with hypoactive sexual desire disorder (HSDD) and those with no female sexual dysfunction (FSD). The SIDI-F is a clinician-rated instrument consisting of 13 items designed to assess HSDD severity in women. The total score ranges from 0 to 51, with higher scores indicating better sexual function. Methods: Data from patients enrolled in a North American nontreatment study and a European nontreatment study were analyzed. Both studies were 4-week, prospective, multicenter trials designed to assess the reliability and validity of the SIDI-F. Only patients with HSDD or no FSD were included in this analysis. Receiver operating characteristics (ROC) analysis was used to determine the ability of the SIDI-F to differentiate between patients with HSDD and those with no FSD at baseline. Results: A total of 428 women were included in this analysis: 174 from North America (HSDD 113, no FSD 61) and 254 from Europe (HSDD 130, no FSD 124). In the North American study, a SIDI-F cutoff score of 33 minimized the difference between sensitivity (94.7%) and specificity (93.4%). In the European study, SIDI-F cutoff scores of both 33 and 34 minimized the difference between sensitivity (95.2%) and specificity (94.4%). Conclusions: In appropriately screened women, a SIDI-F score of ≤33 indicates the presence of HSDD.

Original languageEnglish
Pages (from-to)2191-2195
Number of pages5
JournalJournal of Women's Health
Volume19
Issue number12
DOIs
Publication statusPublished - Dec 1 2010

ASJC Scopus subject areas

  • Medicine(all)

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