TY - JOUR
T1 - Cutting balloon versus conventional balloon angioplasty for the treatment of in-stent restenosis
T2 - Results of the restenosis cutting balloon evaluation trial (RESCUT)
AU - Albiero, Remo
AU - Silber, Sigmund
AU - Di Mario, Carlo
AU - Cernigliaro, Carmelo
AU - Battaglia, Salvatore
AU - Reimers, Bernhard
AU - Frasheri, Arian
AU - Klauss, Volker
AU - Auge, Joseph M.
AU - Rubartelli, Paolo
AU - Morice, Marie Claude
AU - Cremonesi, Alberto
AU - Schofer, Joachim
AU - Bortone, Alessandro
AU - Colombo, Antonio
PY - 2004/3/17
Y1 - 2004/3/17
N2 - Objectives The aim of this trial was to compare cutting balloon angioplasty (CBA) with conventional balloon angioplasty (i.e., percutaneous transluminal coronary angioplasty [PTCA]) for the treatment of patients with coronary in-stent restenosis (ISR). Background Retrospective studies suggest CBA might be superior to conventional PTCA in the treatment of ISR. Methods The Restenosis Cutting Balloon Evaluation Trial (RESCUT) is a multicenter, randomized, prospective European trial including 428 patients with all types of ISR (e.g., focal, multifocal, diffuse, proliferative). Results In both groups, the majority of ISR lesions were shorter than 20 mm. The length of restenotic stents was similar (CBA: 18.6 ± 9.7 mm; PTCA: 18.3 ± 8.7 mm). The number of balloons used to treat ISR was lower in the CBA group: only one balloon was used in 82.3% of CBA cases, compared with 75% of PTCA procedures (p = 0.03). Balloon slippage was less frequent in the CBA group (CBA 6.5%, PTCA 25%; p <0.01). There was a trend toward a lower need for additional stenting in the CBA group (CBA 3.9%, PTCA 8.0%; p = 0.07). At seven-month angiographic follow-up, the binary restenosis rate was not different between the groups (CBA 29.8%, PTCA 31.4%; p = 0.82), with a similar pattern of recurrent restenosis. Clinical events at seven months were also similar. Conclusions Cutting balloon angioplasty did not reduce recurrent ISR and major adverse cardiac events, as compared with conventional PTCA. However, CBA was associated with some procedural advantages, such as use of fewer balloons, less requirement for additional stenting, and a lower incidence of balloon slippage.
AB - Objectives The aim of this trial was to compare cutting balloon angioplasty (CBA) with conventional balloon angioplasty (i.e., percutaneous transluminal coronary angioplasty [PTCA]) for the treatment of patients with coronary in-stent restenosis (ISR). Background Retrospective studies suggest CBA might be superior to conventional PTCA in the treatment of ISR. Methods The Restenosis Cutting Balloon Evaluation Trial (RESCUT) is a multicenter, randomized, prospective European trial including 428 patients with all types of ISR (e.g., focal, multifocal, diffuse, proliferative). Results In both groups, the majority of ISR lesions were shorter than 20 mm. The length of restenotic stents was similar (CBA: 18.6 ± 9.7 mm; PTCA: 18.3 ± 8.7 mm). The number of balloons used to treat ISR was lower in the CBA group: only one balloon was used in 82.3% of CBA cases, compared with 75% of PTCA procedures (p = 0.03). Balloon slippage was less frequent in the CBA group (CBA 6.5%, PTCA 25%; p <0.01). There was a trend toward a lower need for additional stenting in the CBA group (CBA 3.9%, PTCA 8.0%; p = 0.07). At seven-month angiographic follow-up, the binary restenosis rate was not different between the groups (CBA 29.8%, PTCA 31.4%; p = 0.82), with a similar pattern of recurrent restenosis. Clinical events at seven months were also similar. Conclusions Cutting balloon angioplasty did not reduce recurrent ISR and major adverse cardiac events, as compared with conventional PTCA. However, CBA was associated with some procedural advantages, such as use of fewer balloons, less requirement for additional stenting, and a lower incidence of balloon slippage.
KW - %DS
KW - CABG
KW - CBA
KW - CK
KW - Coronary artery bypass graft surgery
KW - Creatine kinase
KW - Cutting balloon angioplasty
KW - In-stent restenosis
KW - Intravascular ultrasound
KW - ISR
KW - IVUS
KW - MACE
KW - Major adverse cardiac events
KW - Minimum lumen diameter
KW - MLD
KW - Percent diameter stenosis
KW - PTCA
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UR - http://www.scopus.com/inward/citedby.url?scp=12144287459&partnerID=8YFLogxK
U2 - 10.1016/j.jacc.2003.09.054
DO - 10.1016/j.jacc.2003.09.054
M3 - Article
C2 - 15028348
AN - SCOPUS:12144287459
VL - 43
SP - 943
EP - 949
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
SN - 0735-1097
IS - 6
ER -