CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development

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43 Citations (Scopus)

Abstract

Chemokines and their receptors are constitutively present in the central nervous system (CNS), expressed in neurons and glial cells. Much evidence suggests that, beyond their involvement in neuroinflammation, these proteins play a role in neurodevelopment and neurophysiological signaling. The goal of this review is to summarize recent information concerning expression, signaling, and function of CXC chemokine receptor in the CNS, with the main focus on the developmental and neuromodulatory actions of chemokines in the cerebellum.

Original languageEnglish
Pages (from-to)559-572
Number of pages14
JournalJournal of NeuroVirology
Volume8
Issue number6
DOIs
Publication statusPublished - Dec 2002

Fingerprint

CXCR Receptors
Central Nervous System
Chemokine Receptors
Chemokines
Neuroglia
Cerebellum
Neurons
Proteins

Keywords

  • Cerebellum
  • CXC chemokine
  • Development
  • Neutrotransmission

ASJC Scopus subject areas

  • Virology
  • Clinical Neurology

Cite this

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