Cyberknife® system: A new therapeutic strategy for sinonasal solitary extramedullary plasmacytoma

E. Cantone, V. Borzillo, A. M. Di Lullo, L. Marano, E. Guadagno, G. Mansueto, R. Di Franco, F. Cammarota, L. Catalano, P. Muto, M. Iengo

Research output: Contribution to journalArticlepeer-review


Sino-nasal solitary extramedullary plasmacytoma (EMP) is a rare neoplasm with unpredictable progression to multiple myeloma. To improve the precision of irradiation delivery, preserving the healthy surrounding tissue and critical structures we used a CyberKnife® for the treatment of sinonasal solitary extramedullary plasmacytoma. We present the first case of sinonasal-EMP treated with CyberKnife®-stereotactic radiotherapy (SRT) with a complete remission without adverse events. Based on the post-Therapeutic results and healthy tissue preservation, we believe that CyberKnife®-SRT represents a good therapeutic option for the treatment of sinonasal-EMP.

Original languageEnglish
Pages (from-to)763-768
Number of pages6
JournalJournal of Biological Regulators and Homeostatic Agents
Issue number3
Publication statusPublished - Jul 1 2017


  • Epistaxisto
  • Plasma cell
  • Plasmacytoma
  • Radiosurgery
  • Sinunasal
  • Stereotactic radiotherapy

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Physiology
  • Immunology
  • Oncology
  • Endocrinology
  • Physiology (medical)
  • Cancer Research


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