Abstract
Long-term cyclosporin A (CsA) administration in dogs was studied with respect to function of the islets of Langerhans. After 3 weeks of immunosuppression with therapeutic doses, the islets were isolated and assessed in vitro for insulin release in response to glucose challenge. Islet tissue retrieved from the CsA-treated animals showed a total insulin output significantly lower than that of the control animals (p
Original language | English |
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Pages (from-to) | 191-193 |
Number of pages | 3 |
Journal | American Journal of Surgery |
Volume | 156 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1988 |
ASJC Scopus subject areas
- Surgery