Cyclosporin a serum and blood levels in marrow graft recipients: Correlation with administered dose, serum creatinine and graft-versus-host disease

A. Bacigalupo; Di Giorgio; F. Frassoni; M. T. VanLint; M. R. Raffo; L. Gogioso; M. Viale; A. M. Marmont

Cyclosporin a serum and blood levels in marrow graft recipients: Correlation with administered dose, serum creatinine and graft-versus-host disease

A. Bacigalupo, Di Giorgio, F. Frassoni, M. T. VanLint, M. R. Raffo, L. Gogioso, M. Viale, A. M. Marmont

Research output: Contribution to journal › Article › peer-review

Abstract

23 patients undergoing marrow transplantation for leukemia or aplastic anemia were given cyclosporin A (CyA) for graft-versus-host disease (GvHD) prophylaxis. A radioimmunoassay was used to monitor CyA serum levels in 13 patients and whole blood levels in 10. Serum creatinine levels were recorded daily until day 30 and then weekly. The severity of acute GvHD was recorded daily for a total of 1,738 patient days. CyA dose was then correlated with CyA serum or blood levels, serum creatinine levels and severity of acute GvHD.

Original language	English
Pages (from-to)	155-162
Number of pages	8
Journal	Acta Haematologica
Volume	72
Issue number	3
Publication status	Published - 1984

Keywords

Bone marrow transplant
Cyclosporin A

ASJC Scopus subject areas

Hematology

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Cyclosporin a serum and blood levels in marrow graft recipients : Correlation with administered dose, serum creatinine and graft-versus-host disease. / Bacigalupo, A.; Giorgio, Di; Frassoni, F.; VanLint, M. T.; Raffo, M. R.; Gogioso, L.; Viale, M.; Marmont, A. M.

In: Acta Haematologica, Vol. 72, No. 3, 1984, p. 155-162.

Research output: Contribution to journal › Article › peer-review

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title = "Cyclosporin a serum and blood levels in marrow graft recipients: Correlation with administered dose, serum creatinine and graft-versus-host disease",

abstract = "23 patients undergoing marrow transplantation for leukemia or aplastic anemia were given cyclosporin A (CyA) for graft-versus-host disease (GvHD) prophylaxis. A radioimmunoassay was used to monitor CyA serum levels in 13 patients and whole blood levels in 10. Serum creatinine levels were recorded daily until day 30 and then weekly. The severity of acute GvHD was recorded daily for a total of 1,738 patient days. CyA dose was then correlated with CyA serum or blood levels, serum creatinine levels and severity of acute GvHD.",

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AU - Bacigalupo, A.

AU - Giorgio, Di

AU - Frassoni, F.

AU - VanLint, M. T.

AU - Raffo, M. R.

AU - Gogioso, L.

AU - Viale, M.

AU - Marmont, A. M.

PY - 1984

Y1 - 1984

N2 - 23 patients undergoing marrow transplantation for leukemia or aplastic anemia were given cyclosporin A (CyA) for graft-versus-host disease (GvHD) prophylaxis. A radioimmunoassay was used to monitor CyA serum levels in 13 patients and whole blood levels in 10. Serum creatinine levels were recorded daily until day 30 and then weekly. The severity of acute GvHD was recorded daily for a total of 1,738 patient days. CyA dose was then correlated with CyA serum or blood levels, serum creatinine levels and severity of acute GvHD.

AB - 23 patients undergoing marrow transplantation for leukemia or aplastic anemia were given cyclosporin A (CyA) for graft-versus-host disease (GvHD) prophylaxis. A radioimmunoassay was used to monitor CyA serum levels in 13 patients and whole blood levels in 10. Serum creatinine levels were recorded daily until day 30 and then weekly. The severity of acute GvHD was recorded daily for a total of 1,738 patient days. CyA dose was then correlated with CyA serum or blood levels, serum creatinine levels and severity of acute GvHD.

KW - Bone marrow transplant

KW - Cyclosporin A

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Cyclosporin a serum and blood levels in marrow graft recipients: Correlation with administered dose, serum creatinine and graft-versus-host disease

Abstract

Keywords

ASJC Scopus subject areas

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